ArticleThe Journal of cell biology1994
Association of nuclear matrix antigens with exon-containing splicing complexes.
Article in The Journal of cell biology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 214 citations in OpenAlex.
- Coordination of nuclear RNA processing by speckle-localized kinase TAOK2.Genes & development · 2026Article
- Stiff matrix-induced KRTAP2-3 expression suppresses ciliogenesis via actin tension-driven chromatin remodeling.Cell death & disease · 2026Article
- Protein kinase C activity modulates nuclear Lamin A/C dynamics in HeLa cells.Scientific reports · 2024Article
- An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis.Development (Cambridge, England) · 2023Article
- Article
- The Ultrastructural Signature of Human Embryonic Stem Cells.Journal of cellular biochemistry · 2017Article
- Coordinated Dynamics of RNA Splicing Speckles in the Nucleus.Journal of cellular physiology · 2016Article
- Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns.Methods (San Diego, Calif.) · 2016Article
- The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex.Genes & development · 2011Article
- Molecular determinants for small Maf protein control of platelet production.Molecular and cellular biology · 2011Article
- The SR protein family.Genome biology · 2009Review
- Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus.Nature reviews. Molecular cell biology · 2009Review
- Defining early steps in mRNA transport: mutant mRNA in myotonic dystrophy type I is blocked at entry into SC-35 domains.The Journal of cell biology · 2007Article
- Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer.Advances in enzyme regulation · 2007Review
- Molecular anatomy of a speckle.The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology · 2006Article
- Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivo.Molecular and cellular biology · 2005Article
- Nucleoskeleton of early bovine embryos and differentiated somatic cells: an ultrastructural and immunocytochemical comparison.Histochemistry and cell biology · 2004Article
- Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression.Oncogene · 2004Review
- In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160.The Journal of cell biology · 2004Article
- Repositioning of muscle-specific genes relative to the periphery of SC-35 domains during skeletal myogenesis.Molecular biology of the cell · 2004Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
mAbs raised against the human nuclear matrix (anti-NM)1 mAbs have been used to investigate the role of nuclear matrix antigens in pre-mRNA processing. The three anti-NM mAbs used in this study recognize antigens that are highly localized to nuclear matrix speckles. Surprisingly, all three of these mAbs preferentially immunoprecipitate splicing complexes containing exon sequences. The anti-NM mAbs efficiently immunoprecipitate the exon product complex but not complexes containing the lariat product after the second step of splicing. Two of the anti-NM mAbs completely inhibit pre-mRNA splicing in vitro. However, none of the anti-NM mAbs appear to recognize factors stably associated with splicing snRNPs. The three anti-NM mAbs predominantly react with distinct high molecular weight antigens, which belong to a class of nuclear proteins that selectively precipitate with Ser-Arg protein-splicing factors in the presence of high Mg2+ concentrations. Immunological, biochemical, and cell biological data indicate that two of the NM antigens are related to the defined set of Ser-Arg proteins. The results suggest the existence of an extended Ser-Arg family as a component of the nuclear matrix.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.