ArticleInfection and immunity1994
Regulation of surface presentation of IcsA, a Shigella protein essential to intracellular movement and spread, is growth phase dependent.
Article in Infection and immunity, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 60 citations in OpenAlex.
- Formate Metabolism in Shigella flexneri and Its Effect on HeLa Cells at Different Stages during the Infectious Process.Microbiology spectrum · 2023Article
- Identification and characterization of a novel lytic peptidoglycan transglycosylase (MltC) in Shigella dysenteriae.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- SurA-like and Skp-like Proteins as Important Virulence Determinants of the Gram Negative Bacterial Pathogens.International journal of molecular sciences · 2022Review
- Article
- Host actin polymerization tunes the cell division cycle of an intracellular pathogen.Cell reports · 2015Article
- Article
- The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility.The Journal of cell biology · 2013Article
- Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spread.Cellular microbiology · 2013Article
- Bruton's tyrosine kinase regulates Shigella flexneri dissemination in HT-29 intestinal cells.Infection and immunity · 2013Article
- Article
- VirF-independent regulation of Shigella virB transcription is mediated by the small RNA RyhB.PloS one · 2012Article
- Outer membrane protein A (OmpA): a new player in shigella flexneri protrusion formation and inter-cellular spreading.PloS one · 2012Article
- The iron-responsive Fur/RyhB regulatory cascade modulates the Shigella outer membrane protease IcsP.Infection and immunity · 2011Article
- Two promoters and two translation start sites control the expression of the Shigella flexneri outer membrane protease IcsP.Archives of microbiology · 2011Article
- The influence of rickettsiologists on post-modern microbiology.Frontiers in cellular and infection microbiology · 2011Review
- IcsA surface presentation in Shigella flexneri requires the periplasmic chaperones DegP, Skp, and SurA.Journal of bacteriology · 2007Article
- Actin-dependent movement of bacterial pathogens.Nature reviews. Microbiology · 2006Review
- Regulation of IcsP, the outer membrane protease of the Shigella actin tail assembly protein IcsA, by virulence plasmid regulators VirF and VirB.Journal of bacteriology · 2004Article
- Mycobacterium marinum escapes from phagosomes and is propelled by actin-based motility.The Journal of experimental medicine · 2003Article
- Shigella flexneri DegP facilitates IcsA surface expression and is required for efficient intercellular spread.Infection and immunity · 2002Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
After lysing the phagocytic vacuole, Shigella spp. accumulate filaments of polymerized actin on their surface at one pole, leading to the formation of actin tails that enable them to move through the cytoplasm. We have recently demonstrated that the Shigella protein IcsA is located at the pole that is adjacent to the growing end of the actin tail (M. B. Goldberg, O. Barzu, C. Parsot, and P. J. Sansonetti, J. Bacteriol. 175:2189-2196, 1993). Not every bacterium that is observed within the cytoplasm has an actin tail. The factors that determine when a bacterium will form a tail are unknown. Here we demonstrate that at the moment of initiation of movement, Shigella spp. are frequently in the process of division. Furthermore, the expression of IcsA on the surface of the bacteria occurs in a growth phase-dependent fashion, suggesting that the surface expression of IcsA per se determines the observed association of bacterial division with movement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.