ArticleInfection and immunity1994
Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells.
Article in Infection and immunity, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 70 citations in OpenAlex.
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- Natural History and Ecology of Interactions BetweenFrontiers in cellular and infection microbiology · 2022Article
- Evolution and Conservation ofFrontiers in microbiology · 2020Review
- RespiratoryInternational journal of molecular sciences · 2018Article
- Bordetella bronchiseptica exploits the complex life cycle of Dictyostelium discoideum as an amplifying transmission vector.PLoS biology · 2017Article
- Type Six Secretion System of Bordetella bronchiseptica and Adaptive Immune Components Limit Intracellular Survival During Infection.PloS one · 2015Article
- Bordetella pertussis-infected human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization and interleukin-23 expression.Infection and immunity · 2005Article
- Bordetella pertussis infection of primary human monocytes alters HLA-DR expression.Infection and immunity · 2004Article
- Respiratory disease in kennelled dogs: serological responses to Bordetella bronchiseptica lipopolysaccharide do not correlate with bacterial isolation or clinical respiratory symptoms.Clinical and diagnostic laboratory immunology · 2003Article
- Primary dendritic cells phagocytose Cryptococcus neoformans via mannose receptors and Fcgamma receptor II for presentation to T lymphocytes.Infection and immunity · 2002Article
- Characterization of a novel intracellularly activated gene from Salmonella enterica serovar typhi.Infection and immunity · 2002Article
- Candida albicans is phagocytosed, killed, and processed for antigen presentation by human dendritic cells.Infection and immunity · 2001Article
- Dendritic cells: immune saviors or Achilles' heel?Infection and immunity · 2001Review
- Reduced virulence of a Bordetella bronchiseptica siderophore mutant in neonatal swine.Infection and immunity · 2001Article
- Fate of Mycobacterium tuberculosis within murine dendritic cells.Infection and immunity · 2001Article
- Phagosome acidification has opposite effects on intracellular survival of Bordetella pertussis and B. bronchiseptica.Infection and immunity · 2000Article
- Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence.Infection and immunity · 2000Article
- Interaction of Salmonella enterica serotype Typhimurium with dendritic cells is defined by targeting to compartments lacking lysosomal membrane glycoproteins.Infection and immunity · 2000Article
- Bordetella pertussis virulence factors affect phagocytosis by human neutrophils.Infection and immunity · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have studied the interaction between the respiratory pathogen Bordetella bronchiseptica and murine spleen dendritic cells, important antigen-presenting cells that are found in the airway epithelium. Wild-type B. bronchiseptica 5376 attached very efficiently to dendritic cells, whereas the bvg mutant ATCC 10580, wild-type strain BB7865, and its spontaneous delta bvgS mutant BB7866 bound less efficiently. However, all tested B. bronchiseptica strains were able to invade dendritic cells and survive intracellularly for at least 72 h. These results suggest that bvg-independent or bvg-downregulated products are involved in the uptake and intracellular survival. Transmission electron microscopic analysis revealed that bacteria grew and replicated intracellularly and were present in typical phagosomes, which fused with lysosomes during the initial infection period. However, in later infection stages some bacteria seemed to escape into an unfused endocytic compartment, where individual bacteria were tightly surrounded by a membrane. The in vitro interaction of B. bronchiseptica with dendritic cells reported here may be relevant to natural infections caused by this organism that lead to chronicity or an altered immune response.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.