Evidence map›Paper›PMID 7953985›Full record

ReviewCalcified tissue international1994

Osteoporosis, sedentary lifestyle, and increasing hip fractures: pathogenic relationship or differential survival bias.

R L McGraw, J E Riggs

Abstract readReview
PubMed Publisher
In one paragraph

Review in Calcified tissue international, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

R L McGrawDepartment of Neurology, West Virginia University School of Medicine, Morgantown.
J E Riggs
West Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis, although a disorder of antiquity, has become more prevalent in developed countries and is a major risk factor for skeletal fracture. Accordingly, the increasing incidence of hip fracture among the elderly within developed nations has been attributed to an increased prevalence of osteoporosis. An increasingly sedentary lifestyle has been suggested as a significant contributing factor for the increased prevalence of osteoporosis. However, differential survival, reflecting changing competing mortality risks, will alter the gene pool of a surviving population cohort. Thus, the gene pool (and hence, disease susceptibilities) of 70-year-old individuals in 1990, for example, should not implicitly be assumed to be the same as 70-year-old individuals in 1950. Consequently, differences in the prevalence of osteoporosis or incidence of hip fracture between current and past elderly cohorts do not necessarily imply differences in environmental risk factors such as levels of physical activity. Instead, variation in competing mortality risks over time may produce differential survival with selection bias and "naturally" lead to increases in the incidence and prevalence of some aging-related disorders such as osteoporosis.

Indexed as

AgedBiasCohort StudiesFemaleHip FracturesHumansLife StyleMaleOsteoporosisRisk FactorsSurvival Analysis

Identifiers

PMID7953985
OpenAlexW2038476728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.