ArticleMammalian genome : official journal of the International Mammalian Genome Society1994
Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in the mouse and human.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 91 citations in OpenAlex.
- Exploring Autosomal Dominant Non-Syndromic Monogenic Obesity: From Genes to Therapy.Current issues in molecular biology · 2026Review
- Melanocortin 4 receptor mutation in obesity.World journal of experimental medicine · 2024Review
- Melanocortin-4 receptor complexity in energy homeostasis,obesity and drug development strategies.Diabetes, obesity & metabolism · 2022Review
- Polymorphisms and mutations in the melanocortin-3 receptor and their relation to human obesity.Biochimica et biophysica acta. Molecular basis of disease · 2017Review
- Effects of Repository Corticotropin Injection on Medication Use in Patients With Rheumatologic Conditions: A Claims Data Study.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2017Article
- 60 YEARS OF POMC: Regulation of feeding and energy homeostasis by α-MSH.Journal of molecular endocrinology · 2016Review
- Melanocortin peptides: potential targets in systemic lupus erythematosus.Inflammation · 2015Review
- The genetics of childhood obesity and interaction with dietary macronutrients.Genes & nutrition · 2013Article
- All bariatric surgeries are not created equal: insights from mechanistic comparisons.Endocrine reviews · 2012Review
- A Common variant near the melanocortin 4 receptor is associated with low-density lipoprotein cholesterol and total cholesterol in the Chinese Han population.Molecular biology reports · 2012Article
- Reciprocal responses of fibroblasts and melanocytes to α-MSH depending on MC1R polymorphisms.Dermato-endocrinology · 2011Article
- Gene-diet interactions in childhood obesity.Current genomics · 2011Article
- Sequence polymorphisms of MC1R gene and their association with depression and antidepressant response.Psychiatric genetics · 2011Article
- The nutritional induction of COUP-TFII gene expression in ventromedial hypothalamic neurons is mediated by the melanocortin pathway.PloS one · 2010Article
- The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.Endocrine reviews · 2010Article
- Body weight is regulated by the brain: a link between feeding and emotion.Molecular psychiatry · 2005Review
- Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair.American journal of human genetics · 2001Article
- Article
- Descriptive analysis of MC4R gene variants associated with obesity listed on ClinVar.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The melanocortin peptides regulate a wide variety of physiological processes, including pigmentation and glucocorticoid production, and also have several activities in the central and peripheral nervous systems. The melanocortin receptor family includes the melanocyte-stimulating hormone receptor (MSH-R), adrenocorticotropic hormone receptor (ACTH-R), and two neural receptors, MC3-R and MC4-R. In the human these receptors map to 16q24 (MSH-R), 18p11.2 (ACTH-R), 20q13.2 (MC3-R), and 18q22 (MC4-R). The corresponding locations in the mouse are 8, 18, and 2; a variant for mapping MC4-R has not yet been identified. The data reported here also show that the neural MC3 receptor maps close to a disease locus for benign neonatal epilepsy in human and near the E1-2 epilepsy susceptibility locus in the mouse.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.