Evidence map›Paper›PMID 7949731›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society1994

Mapping of PCR-based markers for mouse chromosome 4 on a backcross penetrant for the misty (m) mutation.

F T Fiedorek, E S Kay

Abstract read
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In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
  3. Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
  4. Article
  5. Mapping of the MEK kinase gene (Mekk) to mouse chromosome 13 and human chromosome 5.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  6. Mapping of the focal adhesion kinase (Fadk) gene to mouse chromosome 15 and human chromosome 8.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

F T FiedorekDepartment of Medicine, University of North Carolina at Chapel Hill 27599.
E S Kay

Funding

MAPPING AND ISOLATION OF THE DB GENEK08DK001865 · NIDDK · WASHINGTON UNIVERSITY · PI FIEDOREK, FREDERICK T · 1988 to 1990
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MAPPING AND STRUCTURAL ANALYSIS OF OBESITY GENESR01DK044074 · NIDDK · WASHINGTON UNIVERSITY · PI FIEDOREK, FREDERICK T · 1991 to 1994
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NIDDK NIH HHS KO8 DK-01865NIDDK NIH HHS R01 DK-44074
6 · The paper itself

Abstract

A genetic linkage map for mouse Chromosome (Chr) 4 (MMU 4) has been constructed with an intersubspecific backcross between the C57BL/KsJ strain homozygous for the misty (m) coat color locus and the inbred Mus musculus musculus Czech II strain. Several recently developed PCR-based simple sequence length polymorphism (SSLP) markers have been intercalated among gene-based markers including six anchor loci on mouse Chr 4 to assemble this map. Marker order and genetic distances are similar to the composite genetic linkage map compiled from crosses between a variety of other inbred and feral mouse strains. Transmission ratio distortion in favor of feral alleles is apparent for a region of distal MMU 4. In addition, the misty phenotype is more fully penetrant in the present backcross than in other reported interspecific and intersubspecific crosses. Backcrosses employing inbred Mus musculus musculus strains may allow reliable phenotyping and mapping of mouse mutations displaying complex phenotypes with incomplete and/or ambiguous penetrance on other feral genetic backgrounds.

Indexed as

Chromosome MappingMutationAnimalsBase SequenceCrosses, GeneticDNA PrimersFemaleGenetic LinkageGenetic MarkersMaleMiceMice, Inbred C57BLMolecular Sequence DataPolymerase Chain ReactionSkin PigmentationDNA PrimersGenetic Markers

Identifiers

PMID7949731

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.