Evidence map›Paper›PMID 7945186›Full record

ReviewThe Biochemical journal1994

The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices.

R V Iozzo, I R Cohen, S Grässel, A D Murdoch

Abstract readReview
In one paragraph

Review in The Biochemical journal, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed.

  1. Mechanosignaling in Osteoporosis: When Cells Feel the Force.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Production of Extracellular Matrix Proteins in the Cytoplasm ofInternational journal of molecular sciences · 2020
    Article
  11. Article
  12. Review
  13. A role for proteoglycans in vascular disease.Matrix biology : journal of the International Society for Matrix Biology · 2018
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Extracellular Matrix, a Hard Player in Angiogenesis.International journal of molecular sciences · 2016
    Review

49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

R V IozzoDepartment of Pathology and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107.
I R Cohen
S Grässel
A D Murdoch

Funding

NEOPLASTIC MODULATION OF PROTEOGLYCAN METABOLISMR01CA039481 · NCI · UNIVERSITY OF PENNSYLVANIA · PI IOZZO, RENATO V. · 1985 to 2020
$7.1M
The Biology of Perlecan in Cancer and AngiogenesisR01CA047282 · NCI · THOMAS JEFFERSON UNIVERSITY · PI IOZZO, RENATO V. · 1990 to 2019
$5.7M
NCI NIH HHS R01 CA-39481NCI NIH HHS R01 CA-47282
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heparan SulfateHeparan Sulfate ProteoglycansProteoglycansAmino Acid SequenceAnimalsBasement MembraneDiabetic NephropathiesExtracellular MatrixHumansMolecular Sequence DataMusclesNeoplasmsPromoter Regions, GeneticSequence Homology, Amino AcidHeparan SulfateHeparan Sulfate ProteoglycansperlecanProteoglycans

Identifiers

PMID7945186
PMCPMC1137278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.