ArticleMolecular and cellular biology1994
The cellular transcription factor USF cooperates with varicella-zoster virus immediate-early protein 62 to symmetrically activate a bidirectional viral promoter.
Article in Molecular and cellular biology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 103 citations in OpenAlex.
- Differential effects of Sp cellular transcription factors on viral promoter activation by varicella-zoster virus (VZV) IE62 protein.Virology · 2015Article
- Cellular transcription factor YY1 mediates the varicella-zoster virus (VZV) IE62 transcriptional activation.Virology · 2014Article
- Upstream stimulatory factor induces Nr5a1 and Shbg gene expression during the onset of rat Sertoli cell differentiation.Biology of reproduction · 2011Article
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- Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesis.Journal of virology · 2009Article
- HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells.International journal of cancer · 2009Article
- Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation.Journal of virology · 2008Article
- Identification and characterization of the human inhibitor of caspase-activated DNase gene promoter.Apoptosis : an international journal on programmed cell death · 2008Article
- The ubiquitous cellular transcriptional factor USF targets the varicella-zoster virus open reading frame 10 promoter and determines virulence in human skin xenografts in SCIDhu mice in vivo.Journal of virology · 2007Article
- Absence or overexpression of the Varicella-Zoster Virus (VZV) ORF29 latency-associated protein impairs late gene expression and reduces VZV latency in a rodent model.Journal of virology · 2007Article
- Human Immunodeficiency Virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products.Retrovirology · 2006Article
- Posttranslational modification and cell type-specific degradation of varicella-zoster virus ORF29p.Journal of virology · 2006Article
- Generation of a reporter cell line for detection of infectious varicella-zoster virus and its application to antiviral studies.Antimicrobial agents and chemotherapy · 2006Article
- Promoter activation by the varicella-zoster virus major transactivator IE62 and the cellular transcription factor USF.Journal of virology · 2006Article
- The cellular localization pattern of Varicella-Zoster virus ORF29p is influenced by proteasome-mediated degradation.Journal of virology · 2006Article
- A novel archaeal regulatory protein, Sta1, activates transcription from viral promoters.Nucleic acids research · 2006Article
- The gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors.Nucleic acids research · 2006Article
- The DNA element controlling expression of the varicella-zoster virus open reading frame 28 and 29 genes consists of two divergent unidirectional promoters which have a common USF site.Journal of virology · 2004Article
- USF1 and USF2 mediate inhibition of human trophoblast differentiation and CYP19 gene expression by Mash-2 and hypoxia.Molecular and cellular biology · 2003Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The mechanisms governing the function of cellular USF and herpesvirus immediate-early transcription factors are subjects of considerable interest. In this regard, we identified a novel form of coordinate gene regulation involving a cooperative interplay between cellular USF and the varicella-zoster virus immediate-early protein 62 (IE 62). A single USF-binding site defines the potential level of IE 62-dependent activation of a bidirectional viral early promoter of the DNA polymerase and major DNA-binding protein genes. We also report a dominant negative USF-2 mutant lacking the DNA-binding domain that permits the delineation of the biological role of both USF-1 and USF-2 in this activation process. The symmetrical stimulation of the bidirectional viral promoter by IE 62 is achieved at concentrations of USF-1 (43 kDa) or USF-2 (44 kDa) already existing in cells. Our observations support the notion that cellular USF can intervene in and possibly target promoters for activation by a herpesvirus immediate-early protein.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.