ArticleMolecular and cellular biology1994
Multiple products from the shavenbaby-ovo gene region of Drosophila melanogaster: relationship to genetic complexity.
Article in Molecular and cellular biology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Identification of a high-activity and ubiquitous promoter from lepidoptera insect for transgenic applications.Journal of insect science (Online) · 2026Article
- An NF-κB/OVOL2 circuit regulates glucose import and cell survival in non-small cell lung cancer.Cell communication and signaling : CCS · 2022Article
- CRISPR Disruption ofInsects · 2019Article
- Functional characterization of BmOVOs in silkworm, Bombyx mori.BMC genomics · 2019Article
- Comparative transcriptomic analysis of silkworm Bmovo-1 and wild type silkworm ovary.Scientific reports · 2015Article
- Article
- Bmovo-1 regulates ovary size in the silkworm, Bombyx mori.PloS one · 2014Article
- C2H2 zinc finger genes of the Gli, Zic, KLF, SP, Wilms' tumour, Huckebein, Snail, Ovo, Spalt, Odd, Blimp-1, Fez and related gene families from Branchiostoma floridae.Development genes and evolution · 2008Article
- Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice.Genomics · 2002Article
- Sex determination signals control ovo-B transcription in Drosophila melanogaster germ cells.Genetics · 2002Article
- Article
- Characterization of Drosophila OVO protein DNA binding specificity using random DNA oligomer selection suggests zinc finger degeneration.Nucleic acids research · 2000Article
- The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice.Genes & development · 1998Article
- A hotspot for the Drosophila gypsy retroelement in the ovo locus.Nucleic acids research · 1998Article
- Characterization of a human homolog (OVOL1) of the Drosophila ovo gene, which maps to chromosome 11q13.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The Drosophila melanogaster shavenbaby (svb)-ovo gene region is a complex locus, containing two distinct but comutable genetic functions. ovo is required for survival and differentiation of female germ line cells and plays a role in germ line sex determination. In contrast, svb is required in both male and female embryos for the production of epidermal locomotor and sensory structures. Sequences required for the two genetic functions are partially overlapping. ovo corresponds to a previously described germ line-dependent 5.0-kb poly(A)+ mRNA that first appears in the germarium and accumulates in nurse cells during oogenesis. The 5.0-kb mRNA is stored in the egg, but it is rapidly lost in the embryos except for its continued presence in the germ line precursor pole cells. The ovo mRNA predicts a 1,028-amino-acid 110.6-kDa protein homologous with transcription factors. We have identified an embryonic mRNA, 7.1 kb in length, that contains exons partially overlapping those of the 5.0-kb poly(A)+ mRNA. The spatial distribution of this newly discovered transcript during midembryogenesis suggests that it corresponds to the svb function. The arrangement of exons common to the 5.0- and 7.1-kb mRNAs suggests that the Ovo and Svb proteins share DNA-binding specificity conferred by four Cys2-His2 zinc finger motifs but differ functionally in their capacity to interact with other components of the transcription machinery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.