ArticleHuman genetics1994
A polymorphic alpha satellite sequence specific for human chromosome 13 detected by oligonucleotide primed in situ labelling (PRINS).
Article in Human genetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Detection of short repeated genomic sequences on metaphase chromosomes using padlock probes and target primed rolling circle DNA synthesis.BMC molecular biology · 2007Article
- Article
- The peptide nucleic acids (PNAs): introduction to a new class of probes for chromosomal investigation.Chromosoma · 2004Review
- Gamma-heregulin: a fusion gene of DOC-4 and neuregulin-1 derived from a chromosome translocation.Oncogene · 1999Article
- Prenatal detection of chromosome aneuploidies in uncultured chorionic villus samples by FISH.American journal of human genetics · 1996Article
- Rapid chromosome detection in human gametes, zygotes, and preimplantation embryos using the PRINS technique.Journal of assisted reproduction and genetics · 1996Article
- Assessment of aneuploidy for chromosomes 8, 9, 13, 16, and 21 in human sperm by using primed in situ labeling technique.American journal of human genetics · 1996Article
- Direct detection of disomy in human sperm by the PRINS technique.Human genetics · 1996Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The centromeric alpha satellite DNA subfamilies from chromosomes 13 and 21 are almost identical in sequence and cannot be easily distinguished by mean of probes for Southern blot or in situ hybridisation. We have used the oligonucleotide-primed in situ (PRINS) labelling technique with primers defined from the alpha satellite sequence of chromosome 13. One primer was found to label specifically the centromeric region of chromosomes 13 and allowed the detection of a polymorphism between two chromosome 13 homologues in one individual.
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Registered trials
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