ArticleProceedings of the National Academy of Sciences of the United States of America1994
Two Mhc class I and two Mhc class II genes map to the chicken Rfp-Y system outside the B complex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Differing Expression and Potential Immunological Role of C-Type Lectin Receptors of Two Different Chicken Breeds against Low Pathogenic H9N2 Avian Influenza Virus.Pathogens (Basel, Switzerland) · 2024Article
- Article
- Innate immune genes of the chicken MHC and related regions.Immunogenetics · 2022Review
- New vistas unfold: Chicken MHC molecules reveal unexpected ways to present peptides to the immune system.Frontiers in immunology · 2022Review
- Fourth Report on Chicken Genes and Chromosomes 2022.Cytogenetic and genome research · 2022Review
- Chickens as a simple system for scientific discovery: The example of the MHC.Molecular immunology · 2021Article
- Genetic diversity of MHC-B in 12 chicken populations in Korea revealed by single-nucleotide polymorphisms.Immunogenetics · 2020Article
- A simple means for MHC-Y genotyping in chickens using short tandem repeat sequences.Immunogenetics · 2020Article
- A potential nomenclature for the Immuno Polymorphism Database (IPD) of chicken MHC genes: progress and problems.Immunogenetics · 2020Review
- Not all birds have a single dominantly expressed MHC-I gene: Transcription suggests that siskins have many highly expressed MHC-I genes.Scientific reports · 2019Article
- Monitoring conservation effects on a Chinese indigenous chicken breed using major histocompatibility complex B-G gene and DNA Barcodes.Asian-Australasian journal of animal sciences · 2018Article
- Two class I genes of the chicken MHC have different functions: BF1 is recognized by NK cells while BF2 is recognized by CTLs.Immunogenetics · 2018Article
- Characterization of class II β chain major histocompatibility complex genes in a family of Hawaiian honeycreepers: 'amakihi (Hemignathus virens).Immunogenetics · 2016Article
- Brief review of the chicken Major Histocompatibility Complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance.Poultry science · 2016Review
- Sequence of a complete chicken BG haplotype shows dynamic expansion and contraction of two gene lineages with particular expression patterns.PLoS genetics · 2014Article
- Structure and polymorphism of the major histocompatibility complex class II region in the Japanese Crested Ibis, Nipponia nippon.PloS one · 2014Article
- The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV).Immunogenetics · 2013Article
- Canine DLA-79 gene: an improved typing method, identification of new alleles and its role in graft rejection and graft-versus-host disease.Tissue antigens · 2013Article
- Sequencing of the core MHC region of black grouse (Tetrao tetrix) and comparative genomics of the galliform MHC.BMC genomics · 2012Article
- Defining the turkey MHC: identification of expressed class I- and class IIB-like genes independent of the MHC-B.Immunogenetics · 2011Article
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7 authors.
Funding
Abstract
Gene sequences highly similar to major histocompatibility complex (Mhc) class I and class II genes were recently recognized as mapping to a site in the genome of the chicken separate from the Mhc class I, class II, and B-G genes of the major histocompatibility (B) complex. The present study was undertaken to see whether this complex of Mhc-like genes designated as restriction fragment pattern Y (Rfp-Y) might reside in one of three clusters of cosmid clones contained within the molecular map of chicken Mhc genes, since only two of the three clusters can be assigned to the B system. To determine whether the third cluster (cluster II/IV) might contain Rfp-Y, a subclone (18.1) from within cluster II/IV near a polymorphic lectin gene was used to analyze the DNA of families in which Rfp-Y haplotypes are known to be segregating. The restriction fragment polymorphisms revealed by the 18.1 probe were found to segregate in parallel with the restriction fragment polymorphisms defining the Rfp-Y haplotypes, thus establishing the location of Rfp-Y within cosmid cluster II/IV. Two of six Mhc class I genes and two of five Mhc class II genes map to cosmid cluster II/IV, so a substantial fraction of chicken Mhc genes, including at least one that may be expressed, are located in a chromosomal region separate from the B system. In further linkage analyses, Rfp-Y was found to assort independently from more than 400 markers in the present linkage map of the chicken genome.
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