ReviewThe Histochemical journal1993
Update on proliferation-associated antibodies applicable to formalin-fixed paraffin-embedded tissue and their clinical applications.
Review in The Histochemical journal, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 131 citations in OpenAlex.
- Prognostic values of proliferating cell nuclear antigen (PCNA) and Ki-67 for radiotherapy of oesophageal squamous cell carcinomas.British journal of cancer · 1999Trial
- [Clinical Significance and Mechanism of PI3K p110β Overexpression in Non-small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2017Article
- Histologic evaluation of Ki-67 and cleaved caspase-3 expression in feline mammary carcinoma.Journal of feline medicine and surgery · 2017Article
- Fat, fibre and cancer risk in African Americans and rural Africans.Nature communications · 2015Article
- (11)C-Choline and FDG PET/CT Imaging of Primary Cholangiocarcinoma: A Comparative Analysis.Asia Oceania journal of nuclear medicine & biology · 2015Article
- Diet and supplements and their impact on colorectal cancer.Journal of gastrointestinal oncology · 2013Review
- Small particles disrupt postnatal airway development.Journal of applied physiology (Bethesda, Md. : 1985) · 2010Article
- Thymic changes after chorioamnionitis induced by intraamniotic lipopolysaccharide in fetal sheep.American journal of obstetrics and gynecology · 2010Article
- Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon.Journal of anatomy · 2008Article
- Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures.BMC cancer · 2006Article
- A carbohydrate-binding protein, Galectin-1, promotes proliferation of adult neural stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Relationship between persistence of Helicobacter pylori and dysplasia, intestinal metaplasia, atrophy, inflammation, and cell proliferation following partial gastrectomy.Digestive diseases and sciences · 1999Article
- MIB-1 and PC-10 immunostaining for the assessment of proliferative activity in primary acquired melanosis without and with atypia.The British journal of ophthalmology · 1998Article
- [Expression of proliferation markers PCNA and MIB 1 in verrucous squamous epithelial carcinoma of the oral cavity].Mund-, Kiefer- und Gesichtschirurgie : MKG · 1997Article
- Prognostic significance of the proliferative activity in neuroblastoma.The American journal of pathology · 1997Article
- Use of flow cytometry in the analysis of stage III squamous cell carcinoma of the oesophagus and its association with MIB-1.Journal of clinical pathology · 1996Article
- Immunolocalization of basic fibroblast growth factor during wound repair in rat retina after laser photocoagulation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 1996Article
- Ki-67 expression in early prostate cancer and associated pathological lesions.Journal of clinical pathology · 1996Article
- Proliferation in the normal cervix and in preinvasive cervical lesions.Journal of clinical pathology · 1996Article
- Ki-67 immunostaining as a tool in the diagnosis of central cartilage lesions.The Iowa orthopaedic journal · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review provides an update on proliferation-associated antibodies applicable to immunohistochemical techniques in formalin-fixed paraffin-embedded tissue. New insights into proliferating cell nuclear antigen (PCNA) and antibodies to PCNA are presented. The characterization of the protein recognized by the Ki-67 antibody has enabled production of a new range of antibodies (monoclonal and polyclonal) which have immunostaining profiles similar to those of the original antibody. A new proliferation-associated antibody, KiS1, is described. The clinical applications of antibodies to PCNA in human material are summarized, and the limitations of these studies are discussed.
Indexed as
Identifiers
7906685W2078318568What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.