ReviewJournal of bioenergetics and biomembranes1994
Cation transport systems in mitochondria: Na+ and K+ uniports and exchangers.
Review in Journal of bioenergetics and biomembranes, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 80 citations in OpenAlex.
- Proteomic characterization of a foraminiferal test's organic matrix.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- NAD(H) Regulates the Permeability Transition Pore in Mitochondria through an External Site.International journal of molecular sciences · 2021Article
- Mitochondrial Calcification.Immunometabolism · 2021Article
- The Involvement of MgOxidative medicine and cellular longevity · 2017Review
- Modulation of the matrix redox signaling by mitochondrial Ca(2.).World journal of biological chemistry · 2015Review
- Effects of standardized extract of Ginkgo biloba leaves EGb761 on mitochondrial functions: mechanism(s) of action and dependence on the source of mitochondria and respiratory substrate.Journal of bioenergetics and biomembranes · 2014Article
- A panoramic overview of mitochondria and mitochondrial redox biology.Toxicological research · 2014Article
- After half a century mitochondrial calcium in- and efflux machineries reveal themselves.The EMBO journal · 2011Review
- Sensors and regulators of intracellular pH.Nature reviews. Molecular cell biology · 2010Review
- Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume.The Journal of biological chemistry · 2010Article
- Characteristics and possible functions of mitochondrial Ca(2+) transport mechanisms.Biochimica et biophysica acta · 2009Review
- Differential hippocampal protection when blocking intracellular sodium and calcium entry during traumatic brain injury in rats.Journal of neurotrauma · 2008Article
- The role of mitochondria in protection of the heart by preconditioning.Biochimica et biophysica acta · 2007Review
- Apoptosis and oncosis in acute coronary syndromes: assessment and implications.Molecular and cellular biochemistry · 2005Review
- Fatty acids induce chloride permeation in rat liver mitochondria by activation of the inner membrane anion channel (IMAC).Journal of bioenergetics and biomembranes · 2004Article
- Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria.The Journal of physiology · 2003Article
- Closure of the yeast mitochondria unspecific channel (YMUC) unmasks a Mg2+ and quinine sensitive K+ uptake pathway in Saccharomyces cerevisiae.Journal of bioenergetics and biomembranes · 2002Article
- Transport properties of the calcium ionophore ETH-129.Biophysical journal · 2001Article
- Pathophysiological and protective roles of mitochondrial ion channels.The Journal of physiology · 2000Review
- Na+/K+-ATPase inhibition during cardiac myocyte swelling: involvement of intracellular pH and Ca2+.Molecular and cellular biochemistry · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is now well established that mitochondria contain three antiporters that transport monovalent cations. A latent, allosterically regulated K+/H+ antiport appears to serve as a cation-extruding device that helps maintain mitochondrial volume homeostasis. An apparently unregulated Na+/H+ antiport keeps matrix [Na+] low and the Na(+)-gradient equal to the H(+)-gradient. A Na+/Ca2+ antiport provides a Ca(2+)-extruding mechanism that permits the mitochondrion to regulate matrix [Ca2+] by balancing Ca2+ efflux against influx on the Ca(2+)-uniport. All three antiports have well-defined physiological roles and their molecular properties and regulatory features are now being determined. Mitochondria also contain monovalent cation uniports, such as the recently described ATP- and glibenclamide-sensitive K+ channel and ruthenium red-sensitive uniports for Na+ and K+. A physiological role of such uniports has not been established and their properties are just beginning to be defined.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.