ArticleJournal of bacteriology1995
Coordinate cell cycle control of a Caulobacter DNA methyltransferase and the flagellar genetic hierarchy.
Article in Journal of bacteriology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 75 citations in OpenAlex.
- Epigenetic Phase Variation in Bacterial Adaptation to Environmental Stress: A Narrative Review.Current microbiology · 2026Review
- Comparison of CcrM-dependent methylation inJournal of bacteriology · 2024Article
- Comparison of CcrM-dependent methylation inbioRxiv : the preprint server for biology · 2024Article
- Synchronized Swarmers and Sticky Stalks: Caulobacter crescentus as a Model for Bacterial Cell Biology.Journal of bacteriology · 2023Review
- Transcriptional rewiring of the GcrA/CcrM bacterial epigenetic regulatory system in closely related bacteria.PLoS genetics · 2021Article
- Article
- Reciprocal control of motility and biofilm formation by the PdhS2 two-component sensor kinase of Agrobacterium tumefaciens.Microbiology (Reading, England) · 2019Article
- Article
- Identification of essential alphaproteobacterial genes reveals operational variability in conserved developmental and cell cycle systems.Molecular microbiology · 2014Article
- The functions of DNA methylation by CcrM in Caulobacter crescentus: a global approach.Nucleic acids research · 2014Article
- Effect of a ctrA promoter mutation, causing a reduction in CtrA abundance, on the cell cycle and development of Caulobacter crescentus.BMC microbiology · 2013Article
- Analysis of the CtrA pathway in Magnetospirillum reveals an ancestral role in motility in alphaproteobacteria.Journal of bacteriology · 2012Article
- The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner.Nucleic acids research · 2012Article
- Polar remodeling and histidine kinase activation, which is essential for Caulobacter cell cycle progression, are dependent on DNA replication initiation.Journal of bacteriology · 2010Article
- Getting in the loop: regulation of development in Caulobacter crescentus.Microbiology and molecular biology reviews : MMBR · 2010Review
- System-level design of bacterial cell cycle control.FEBS letters · 2009Review
- Complex regulatory pathways coordinate cell-cycle progression and development in Caulobacter crescentus.Advances in microbial physiology · 2009Review
- A quantitative study of the division cycle of Caulobacter crescentus stalked cells.PLoS computational biology · 2008Article
- Epigenetic gene regulation in the bacterial world.Microbiology and molecular biology reviews : MMBR · 2006Article
- A parA homolog selectively influences positioning of the large chromosome origin in Vibrio cholerae.Journal of bacteriology · 2006Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The expression of the Caulobacter ccrM gene and the activity of its product, the M.Ccr II DNA methyltransferase, are limited to a discrete portion of the cell cycle (G. Zweiger, G. Marczynski, and L. Shapiro, J. Mol. Biol. 235:472-485, 1994). Temporal control of DNA methylation has been shown to be critical for normal development in the dimorphic Caulobacter life cycle. To understand the mechanism by which ccrM expression is regulated during the cell cycle, we have identified and characterized the ccrM promoter region. We have found that it belongs to an unusual promoter family used by several Caulobacter class II flagellar genes. The expression of these class II genes initiates assembly of the flagellum just prior to activation of the ccrM promoter in the predivisional cell. Mutational analysis of two M.Ccr II methylation sites located 3' to the ccrM promoter suggests that methylation might influence the temporally controlled inactivation of ccrM transcription. An additional parallel between the ccrM and class II flagellar promoters is that their transcription responds to a cell cycle DNA replication checkpoint. We propose that a common regulatory system coordinates the expression of functionally diverse genes during the Caulobacter cell cycle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.