ArticleGenetics1994
A genetic linkage map of the mouse using restriction landmark genomic scanning (RLGS).
Article in Genetics, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 65 citations in OpenAlex.
- The application of restriction landmark genome scanning method for surveillance of non-mendelian inheritance in f(1) hybrids.Comparative and functional genomics · 2009Article
- An AscI boundary library for the studies of genetic and epigenetic alterations in CpG islands.Genome research · 2002Article
- Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage.Mammalian genome : official journal of the International Mammalian Genome Society · 1998Article
- Linkage map of Syrian hamster with restriction landmark genomic scanning.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Studies of the inheritance of human ribosomal DNA variants detected in two-dimensional separations of genomic restriction fragments.Genetics · 1996Article
- Restriction landmark cDNA scanning (RLCS): a novel cDNA display system using two-dimensional gel electrophoresis.Nucleic acids research · 1996Article
- Structural variation of the pseudoautosomal region between and within inbred mouse strains.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Direct detection and isolation of restriction landmark genomic scanning (RLGS) spot DNA markers tightly linked to a specific trait by using the RLGS spot-bombing method.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
We have developed a multiplex method of genome analysis, restriction landmark genomic scanning (RLGS) that has been used to construct genetic maps in mice. Restriction landmarks are end-labeled restriction fragments of genomic DNA that are separated by using high resolution, two-dimensional gel electrophoresis identifying as many as two thousand landmark loci in a single gel. Variation for several hundred of these loci has been identified between laboratory strains and between these strains and Mus spretus. The segregation of more than 1100 RLGS loci has been analyzed in recombinant inbred (RI) strains and in two separate interspecific genetic crosses. Genetic maps have been derived that link 1045 RLGS loci to reference loci on all of the autosomes and the X chromosome of the mouse genome. The RLGS method can be applied to genome analysis in many different organisms to identify genomic loci because it uses end-labeling of restriction landmarks rather than probe hybridization. Different combinations of restriction enzymes yield different sets of RLGS loci providing expanded power for genetic mapping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.