ArticleCell and tissue research1995
Heterogeneity of smooth muscle-associated proteins in mammalian brain microvasculature.
Article in Cell and tissue research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- How Nitric Oxide Hindered the Search for Hemoglobin-Based Oxygen Carriers as Human Blood Substitutes.International journal of molecular sciences · 2023Review
- Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy.Investigative ophthalmology & visual science · 2013Article
- Article
- Perivascular cells of the supraspinatus tendon express both tendon- and stem cell-related markers.Histochemistry and cell biology · 2009Article
- Dynamic magnetic resonance imaging of cerebral blood flow using arterial spin labeling.Methods in molecular biology (Clifton, N.J.) · 2009Article
- Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis.Histochemistry and cell biology · 2008Article
- Rat meningeal and brain microvasculature pericytes co-express the vesicular glutamate transporters 2 and 3.Neuroscience letters · 2008Article
- Differential expression of splicing variants of the human caldesmon gene (CALD1) in glioma neovascularization versus normal brain microvasculature.The American journal of pathology · 2004Article
- Dissociation of spikes, synaptic activity, and activity-dependent increments in rat cerebellar blood flow by tonic synaptic inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Brain function and neurophysiological correlates of signals used in functional neuroimaging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Review
- [The blood-brain barrier: a specialty of cerebral microcirculation systems].Die Naturwissenschaften · 1996Review
- Physiology of angiogenesis.Journal of neuro-oncologyReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the brain, the microvascular system is composed of endothelial cells surrounded by a layer of pericytes. The lack of smooth muscle cells in this tissue suggests that any contractile function must be performed by one or both of these cell types. The present study was undertaken in order to identify cells in terminal blood vessels that contain smooth muscle-like contractile machinery. Endothelial cells were reactive with antibodies against smooth muscle myosin but showed no other smooth muscle-related features. In contrast, pericytes of intact microvessels showed a pattern of protein expression similar to that of smooth muscle cells. Pericytes also behaved in tissue culture like cultured smooth muscle cells, with regard to the changes in expression of smooth muscle-related proteins. These data confirm the close relationship between smooth muscle cells and pericytes, and point to their contractile function in the brain microvessels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.