ArticlePflugers Archiv : European journal of physiology1994
Identification of single transiently opening ("A-type") K channels in guinea-pig colonic myocytes.
Article in Pflugers Archiv : European journal of physiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 16 citations in OpenAlex.
- Voltage dependent potassium channel remodeling in murine intestinal smooth muscle hypertrophy induced by partial obstruction.PloS one · 2014Article
- Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels.Pulmonary circulation · 2011Article
- Effects of nitric oxide (NO) and NO donors on the membrane conductance of circular smooth muscle cells of the guinea-pig proximal colon.British journal of pharmacology · 1996Article
- Mechanism of inhibition of delayed rectifier K+ current by 4-aminopyridine in rabbit coronary myocytes.The Journal of physiology · 1996Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two K+ channel populations were identified in depolarized cell-attached membrane patches of myocytes freshly dispersed from the circular smooth muscle of guinea-pig proximal colon. First, a large-conductance (150 pS) Ca(2+)-activated K+ channel which was non-inactivating and sensitive to blockade by tetraethylammonium (TEA, 0.5-5 mM); and second, a smaller conductance K+ channel which opened and closed within 100 ms, was insensitive to TEA (0.5-5 mM), but was blocked by 5 mM 4-aminopyridine (4-AP) or maintained depolarization, and which had a unitary conductance of 12-13 pS. The averaged time course of these smaller conductance K+ channels closely resembled the time course of the 4-AP-sensitive, Ca(2+)-insensitive transient outward K+ current recorded in the whole-cell recording mode.
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