Evidence map›Paper›PMID 7887886›Full record

ArticleThe Biochemical journal1995

Cloning and expression of protein tyrosine phosphatase-like protein derived from a rat pheochromocytoma cell line.

Y Kambayashi, K Takahashi, S Bardhan, T Inagami

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 14 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Y KambayashiDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232.
K Takahashi
S Bardhan
T Inagami
Vanderbilt University · US

Funding

TISSUE RENIN AND ANGIOTENSIN--FORMATION AND FUNCTIONP50HL014192 · NHLBI · VANDERBILT UNIVERSITY · 1985 to 1995
–
NHLBI NIH HHS HL07323NHLBI NIH HHS HL14192NHLBI NIH HHS HL35234
6 · The paper itself

Abstract

A novel protein [designated protein tyrosine phosphatase-like protein (PTPLP)] which is distantly related to receptor-type protein tyrosine phosphatases (PTPases) was cloned from a rat pheochromocytoma cell line. The PTPLP was detected exclusively in the brain. Overexpression of the PTPLP decreased the basal PTPase activity of COS-7 cells for Raytide. These results suggest that PTPLP may function as a negative regulator of PTPases in neuronal tissues.

Indexed as

Cloning, MolecularGene ExpressionAdrenal Gland NeoplasmsAmino Acid SequenceAnimalsBase SequenceBlotting, NorthernDNAGlycosylationMembrane ProteinsMolecular Sequence DataNerve Tissue ProteinsPheochromocytomaPolymerase Chain ReactionRatsReceptor-Like Protein Tyrosine Phosphatases, Class 8DNAMembrane ProteinsNerve Tissue ProteinsPtprn protein, ratReceptor-Like Protein Tyrosine Phosphatases, Class 8RNA, Messenger

Identifiers

PMID7887886
PMCPMC1136525
OpenAlexW2239335987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.