Transgenic models of retinoblastoma: what they tell us about its cause and treatment.

D M Albert, A E Griep, P F Lambert, K A Howes, J J Windle, J G Lasudry

Abstract read

In one paragraph

Article in Transactions of the American Ophthalmological Society, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it

0cells of the map it votes in

7citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

Progress in Small Molecule Therapeutics for the Treatment of Retinoblastoma.Mini reviews in medicinal chemistry · 2016
Review
Transgenic Models in Retinoblastoma Research.Ocular oncology and pathology · 2015
Review
Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.Neural development · 2009
Article
Lack of effect of SU1498, an inhibitor of vascular endothelial growth factor receptor-2, in a transgenic murine model of retinoblastoma.The open ophthalmology journal · 2008
Article
Metastatic and nonmetastatic models of retinoblastoma.The American journal of pathology · 2000
Article
Multiple changes in oncogenes and tumor suppressor genes in human retinoblastoma.Transactions of the American Ophthalmological Society · 1996
Article
Penetration of Carbon Nanotubes into the Retinoblastoma Tumor after Intravitreal Injection in LHJournal of ophthalmic & vision research
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

D M AlbertDepartment of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison.

A E Griep

P F Lambert

K A Howes

J J Windle

J G Lasudry

Funding

THE MOLECULAR BIOLOGY OF RETINOBLASTOMAR01EY001917 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ALBERT, DANIEL M · 1985 to 2006

$2.2M

TREATMENT OF RETINOBLASTOMA IN THE TRANSGENIC MOUSEF05TW004797 · FIC · UNIVERSITY OF WISCONSIN MADISON · PI LASUDRY, JACQUES G · 1992 to 1993

–

FIC NIH HHS TW04797NEI NIH HHS EY01917

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAnimalsAntigens, Polyomavirus TransformingEye NeoplasmsEye ProteinsFemaleGenes, p53Genes, RetinoblastomaLuteinizing HormoneMaleMiceMice, TransgenicPapillomaviridaeRetinoblastomaRetinol-Binding ProteinsRetinol-Binding Proteins, InterstitialAntigens, Polyomavirus TransformingEye ProteinsLuteinizing HormoneRetinol-Binding ProteinsRetinol-Binding Proteins, Interstitial

Identifiers

PMID7886874

PMCPMC1298518

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.