Evidence map›Paper›PMID 7883903›Full record

ArticleJournal of clinical microbiology1994

Optimization of quantitative culture assay for human immunodeficiency virus from plasma. Plasma Viremia Group Laboratories of the AIDS Clinical Trials Group (National Institute of Allergy and Infectious Diseases).

J L Lathey, S A Fiscus, S Rasheed, J C Kappes, B P Griffith, T Elbeik, S A Spector, P S Reichelderfer

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J L LatheyDepartment of Pediatrics, University of California, San Diego, La Jolla 92093.
S A Fiscus
S Rasheed
J C Kappes
B P Griffith
T Elbeik
S A Spector
P S Reichelderfer

Funding

Zonisamide in Patients with Neuropathic Pain Associated with Diabetic NeuropathyM01RR000046 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MUENZER, JOSEPH J. · 1985 to 2008
$38.5M
WOMEN'S HEALTH AGENDAU01AI025868 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ERON, JOSEPH J. · 1987 to 2006
$14.9M
PEDIATRIC AIDS CLINICAL TRIALS GROUPU01AI027563 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SPECTOR, STEPHEN A · 1988 to 2006
$6.4M
NCRR NIH HHS RR 00046NIAID NIH HHS AI25868NIAID NIH HHS AI27563
6 · The paper itself

Abstract

Experimental conditions essential to a simple, reproducible, quantitative human immunodeficiency virus plasma assay were determined. Five parameters were evaluated: length of culture, reproducibility, assay dilution schema, washing procedures, and anticoagulant usage. The recommended quantitative plasma assay utilizes undiluted citrated plasma cultured with peripheral blood mononuclear cells for 14 days with fivefold dilutions and a medium change on day 1 with no washing.

Indexed as

Citric AcidMicrobiological TechniquesBloodGlucoseHIV-1HIV SeropositivityHumansReproducibility of Resultsacid citrate dextroseCitric AcidGlucose

Identifiers

PMID7883903
PMCPMC264230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.