ArticleGut1995
Rat intestinal mucosal responses to a microbial flora and different diets.
Article in Gut, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 148 citations in OpenAlex.
- Bacteria colonization and gene expression related to immune function in colon mucosa is associated with growth in neonatal calves regardless of live yeast supplementation.Journal of animal science and biotechnology · 2024Article
- Characterization of the preweaned Holstein calf fecal microbiota prior to, during, and following resolution of uncomplicated gastrointestinal disease.Frontiers in microbiology · 2024Article
- Impact of structurally diverse polysaccharides on colonic mucin O-glycosylation and gut microbiota.NPJ biofilms and microbiomes · 2023Article
- Red propolis extract as a natural ionophore for confined sheep: performance and morphological and histopathological changes.Tropical animal health and production · 2023Article
- Special Issue on the "Regulation and Physiopathology of the Gut Barrier".International journal of molecular sciences · 2022Article
- Intestinal Morphometric Changes Induced by a Western-Style Diet in Wistar Rats and GSPE Counter-Regulatory Effect.Nutrients · 2022Article
- The Effects of Different Forms of Butyric Acid on the Performance of Turkeys, Carcass Quality, Incidence of Footpad Dermatitis and Economic Efficiency.Animals : an open access journal from MDPI · 2022Article
- Intestinal Barrier in Human Health and Disease.International journal of environmental research and public health · 2021Review
- Microbial influences on gut development and gut-brain communication.Development (Cambridge, England) · 2021Review
- Resistant Starches and Non-Communicable Disease: A Focus on Mediterranean Diet.Foods (Basel, Switzerland) · 2021Review
- A Narrative Review on the Unexplored Potential of Colostrum as a Preventative Treatment and Therapy for Diarrhea in Neonatal Dairy Calves.Animals : an open access journal from MDPI · 2021Review
- Mucin-Type O-Glycans: Barrier, Microbiota, and Immune Anchors in Inflammatory Bowel Disease.Journal of inflammation research · 2021Review
- Feeding Pre-weaned Calves With Waste Milk Containing Antibiotic Residues Is Related to a Higher Incidence of Diarrhea and Alterations in the Fecal Microbiota.Frontiers in veterinary science · 2021Article
- Changes in dietary fiber intake in mice reveal associations between colonic mucinGut microbes · 2020Article
- Single or Combined Applications of Zinc and Multi-strain Probiotic on Intestinal Histomorphology of Broilers Under Cyclic Heat Stress.Probiotics and antimicrobial proteins · 2020Article
- Effect of Dietary Supplementation of Zinc and Multi-Microbe Probiotic on Growth Traits and Alteration of Intestinal Architecture in Broiler.Probiotics and antimicrobial proteins · 2019Article
- Effects of Different Diets on Microbiota in The Small Intestine Mucus and Weight Regulation in Rats.Scientific reports · 2019Article
- Effects of chlorogenic acid, epicatechin gallate, and quercetin on mucin expression and secretion in the Caco-2/HT29-MTX cell model.Food science & nutrition · 2019Article
- Maintenance of Distal Intestinal Structure in the Face of Prolonged Fasting: A Comparative Examination of Species From Five Vertebrate Classes.Anatomical record (Hoboken, N.J. : 2007) · 2017Article
- Interactions of Intestinal Bacteria with Components of the Intestinal Mucus.Frontiers in cellular and infection microbiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of diet on the histochemical composition of intestinal mucosubstances and the morphology of the villi and crypts were investigated by comparing the data of germ free and conventionally maintained rats fed either a purified diet or a commercial diet. The influence of intestinal microflora was evaluated by comparing the germ free rats and those harbouring either a conventional rat flora or a human microbial flora. In both germ free rats and those maintained conventionally, feeding a purified diet resulted in shallower crypts in the small intestine but deeper crypts in the large intestine compared with their counterparts fed on the commercial diet. The preliminary data obtained with association of human flora showed a reduction of the villus height and crypt depth in the small intestine and, to some extent, the amount of neutral mucins in the goblet cells of both small and large intestine and an increase in the amount of sulphated mucins in the large intestine. In rats given the commercial diet the periodic acid Schiff staining for neutral mucins was more intense in the upper crypts of the small intestine than in the lower crypts, and to a lesser extent in the upper crypts of the large intestine. These results provide evidence that the dietary composition, microbial flora, as well as the interactions between the dietary constituents and microbial flora change the mucosal architecture and the mucus composition and therefore alter the functional characteristics of the intestinal tract.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.