ArticleBritish journal of cancer1995
Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome.
Article in British journal of cancer, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 130 citations in OpenAlex.
- Comprehensive analysis of CXCL14 uncovers its role during liver metastasis in colon cancer.BMC gastroenterology · 2023Article
- Severe neonatal anemia increases intestinal permeability by disrupting epithelial adherens junctions.American journal of physiology. Gastrointestinal and liver physiology · 2020Article
- The Gene Expression Profile and DNA Methylation Pattern of CDH1 and DNMT1 Genes in Acute Promyelocytic Leukemia (APL).Reports of biochemistry & molecular biology · 2020Article
- Blood serum levels of E-cadherin in patients with colorectal cancer.Przeglad gastroenterologiczny · 2017Article
- Tumour-suppressive function of SIRT4 in human colorectal cancer.British journal of cancer · 2015Article
- Loss of E-cadherin promotes migration and invasion of cholangiocarcinoma cells and serves as a potential marker of metastasis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- Tissue-based biomarkers predicting outcomes in metastatic colorectal cancer: a review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2014Review
- Positive expression of LSD1 and negative expression of E-cadherin correlate with metastasis and poor prognosis of colon cancer.Digestive diseases and sciences · 2013Article
- Meeting the biologic challenge of colorectal metastases.Clinical & experimental metastasis · 2012Review
- Establishment of animal model for the analysis of cancer cell metastasis during radiotherapy.Radiation oncology (London, England) · 2012Article
- Prognostic significance of transforming growth factor beta (TGF-β) signaling axis molecules and E-cadherin in colorectal cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2012Article
- Interferon-β signaling contributes to Ras transformation.PloS one · 2011Article
- Epithelial-mesenchymal transition in cancer development and its clinical significance.Cancer science · 2010Review
- Article
- E-cadherin but not beta-catenin expression is decreased in laryngeal biopsies from patients with laryngopharyngeal reflux.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2008Article
- Expression patterns of dysadherin and E-cadherin in lymph node metastases of colorectal carcinoma.Virchows Archiv : an international journal of pathology · 2006Article
- cDNA array analysis for prediction of hepatic metastasis of colorectal carcinoma.Surgery today · 2006Article
- A subset of high-grade pulmonary neuroendocrine carcinomas shows up-regulation of matrix metalloproteinase-7 associated with nuclear beta-catenin immunoreactivity, independent of EGFR and HER-2 gene amplification or expression.Virchows Archiv : an international journal of pathology · 2005Article
- [Current status of the prognostic value of molecular markers in patients with colorectal cancer and the prediction of response to adjuvant therapy].Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2005Review
- Connexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in culture.Breast cancer research : BCR · 2005Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A series of colorectal carcinomas (n = 49) resected from patients with known clinical outcomes were analysed for E-cadherin expression using in situ hybridisation to measure mRNA. Patients surviving 5 years or longer (n = 31) exhibited significantly higher levels of E-cadherin mRNA than those surviving less than 5 years (n = 18, P = 0.003). These preliminary results from this small sample suggest that E-cadherin expression may be a useful prognostic marker in colorectal cancer patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.