Evidence map›Paper›PMID 7868134›Full record

ArticleHuman genetics1995

Localization of the human soluble epoxide hydrolase gene (EPHX2) to chromosomal region 8p21-p12.

C Larsson, I White, C Johansson, A Stark, J Meijer

Abstract read
PubMed Publisher
In one paragraph

Article in Human genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  9. Missense Genetic Polymorphisms of Microsomal (Neuropsychiatric disease and treatment · 2020
    Article
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  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Epoxyeicosatrienoic acids and cardioprotection: the road to translation.Journal of molecular and cellular cardiology · 2014
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

C LarssonDepartment of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden.
I White
C Johansson
A Stark
J Meijer
Swedish University of Agricultural Sciences · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epoxide hydrolases have an important function in organisms in that they catalyze the transformation of potentially toxic or carcinogenic epoxides into the corresponding diols. In this study, the chromosomal localization was determined for the human gene encoding soluble epoxide hydrolase. A polymerase chain reaction fragment corresponding to the C-terminal region of the mouse protein was used to isolate a cosmid clone from a human genomic library. By fluorescence in situ hybridization to metaphase chromosomes, the soluble epoxide hydrolase gene was then localized to chromosomal region 8p21-p12.

Indexed as

Chromosomes, Human, Pair 8AnimalsBase SequenceBlotting, SouthernDNA PrimersDNA ProbesEpoxide HydrolasesHumansIn Situ Hybridization, FluorescenceMiceMolecular Sequence DataDNA PrimersDNA ProbesEpoxide Hydrolases

Identifiers

PMID7868134
OpenAlexW2058311238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.