ArticleJournal of bacteriology1995
Identification of genes negatively regulated by Fis: Fis and RpoS comodulate growth-phase-dependent gene expression in Escherichia coli.
Article in Journal of bacteriology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 121 citations in OpenAlex.
- Diadenosine tetraphosphate modulated quorum sensing in bacteria treated with kanamycin.BMC microbiology · 2023Article
- Expression of acetaldehyde dehydrogenase (aldB) improved ethanol production from xylose by the ethanologenic Escherichia coli RM10.World journal of microbiology & biotechnology · 2020Article
- GermlineCold Spring Harbor molecular case studies · 2018Article
- LapF and Its Regulation by Fis Affect the Cell Surface Hydrophobicity of Pseudomonas putida.PloS one · 2016Article
- The rpoS gene is predominantly inactivated during laboratory storage and undergoes source-sink evolution in Escherichia coli species.Journal of bacteriology · 2014Article
- Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspective.Microbiology and molecular biology reviews : MMBR · 2013Review
- The type VI secretion system encoded in Salmonella pathogenicity island 19 is required for Salmonella enterica serotype Gallinarum survival within infected macrophages.Infection and immunity · 2013Article
- The role of the local environment of engineered Tyr to Trp substitutions for probing the denaturation mechanism of FIS.Protein science : a publication of the Protein Society · 2011Article
- Article
- Mycoplasma pneumoniae Community Acquired Respiratory Distress Syndrome toxin expression reveals growth phase and infection-dependent regulation.Molecular microbiology · 2010Article
- Functional characterization of the Escherichia coli Fis-DNA binding sequence.Journal of molecular biology · 2008Article
- Physiological effects of Crl in Salmonella are modulated by sigmaS level and promoter specificity.Journal of bacteriology · 2007Article
- Dynamic state of DNA topology is essential for genome condensation in bacteria.The EMBO journal · 2006Article
- DksA is required for growth phase-dependent regulation, growth rate-dependent control, and stringent control of fis expression in Escherichia coli.Journal of bacteriology · 2006Article
- DNA microarray and proteomic analyses of the RpoS regulon in Geobacter sulfurreducens.Journal of bacteriology · 2006Article
- Common and variable contributions of Fis residues to high-affinity binding at different DNA sequences.Journal of bacteriology · 2006Article
- Isolation and characterization of an aldehyde dehydrogenase encoded by the aldB gene of Escherichia coli.Journal of bacteriology · 2005Article
- Microarray analysis of RpoS-mediated gene expression in Escherichia coli K-12.Molecular genetics and genomics : MGG · 2004Article
- Genetic evidence that Legionella pneumophila RpoS modulates expression of the transmission phenotype in both the exponential phase and the stationary phase.Infection and immunity · 2004Article
- Growth phase-dependent regulation and stringent control of fis are conserved processes in enteric bacteria and involve a single promoter (fis P) in Escherichia coli.Journal of bacteriology · 2004Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Fis is a nucleoid-associated protein in Escherichia coli that has been shown to regulate recombination, replication, and transcription reactions. It is expressed in a transient manner under batch culturing conditions such that high levels are present during early exponential phase and low levels are present during late exponential phase and stationary phase. We have screened a random collection of transposon-induced lac fusions for those which give decreased expression in the presence of Fis. Thirteen different Fis-repressed genes were identified, including glnQ (glutamine high-affinity transport), mglA (methyl-galactoside transport), xylF (D-xylose-binding protein), sdhA (succinate dehydrogenase flavoprotein subunit), and a newly identified aldehyde dehydrogenase, aldB. The LacZ expression patterns revealed that many of the fusions were maximally expressed at different stages of growth, including early log phase, mid- to late log phase, and stationary phase. The expression of some of the late-exponential- and stationary-phase genes was dependent on the RpoS sigma factor, whereas that of others was affected negatively by RpoS. We conclude that Fis negatively regulates a diverse set of genes and that RpoS can function to both activate and inhibit the expression of specific genes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.