ArticleHuman genetics1995
Localization of the gene for a novel human adenylyl cyclase (ADCY7) to chromosome 16.
Article in Human genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 38 citations in OpenAlex.
- Integrated bioinformatics investigation of adenylyl cyclase family co-expression network in bladder cancer followed by preliminary validation of member 2 (Translational cancer research · 2024Article
- Physiological roles of mammalian transmembrane adenylyl cyclase isoforms.Physiological reviews · 2022Review
- CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.Oncotarget · 2018Article
- ADCY7 supports development of acute myeloid leukemia.Biochemical and biophysical research communications · 2015Article
- The Mechanism Research of Qishen Yiqi Formula by Module-Network Analysis.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Molecular cloning, sequence identification, and gene expression analysis of bovine ADCY2 gene.Molecular biology reports · 2014Article
- Novel pathways in the pathobiology of human abdominal aortic aneurysms.Pathobiology : journal of immunopathology, molecular and cellular biology · 2013Article
- Sex-specific role for adenylyl cyclase type 7 in alcohol dependence.Biological psychiatry · 2011Article
- A sex-specific role of type VII adenylyl cyclase in depression.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- The gene encoding adenylyl cyclase VII is located in central mouse chromosome 8.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
A novel form of human adenylyl cyclase (ADCY7) has been discovered in the human erythroleukemia cell line (HEL). This cell line has been widely used as a model for studies of the characteristics of human platelets. Data from HEL cells suggests that ADCY7 may be the major AC form in human platelets. In the current study polymerase chain reaction (PCR) techniques coupled with use of human/rodent somatic hybrid panels and a yeast artificial chromosome (YAC) library were used to determine the chromosomal localization of the gene (adcy7) for ADCY7 enzyme. A 251-bp product from the 3' untranslated region of human adcy7 was amplified for PCR mapping and the results localize the adcy7 gene to region 16q12-16q13 of the human genome. The AC enzyme family is characterized by the presence of 12 membrane-spanning domains in its sequences, and this chromosomal region is known to contain other genes coding for proteins characterized by 12 membrane-spanning domains.
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Registered trials
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