ArticleJournal of molecular neuroscience : MN1994
Distribution of the vesicular acetylcholine transporter (VAChT) in the central and peripheral nervous systems of the rat.
Article in Journal of molecular neuroscience : MN, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 106 citations in OpenAlex.
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- The Local Paracrine Actions of the Pancreatic α-Cell.Diabetes · 2020Review
- Neurochemical organization of the ventral striatum's olfactory tubercle.Journal of neurochemistry · 2020Review
- PET Imaging of Perceptual Learning-Induced Changes in the Aged Rodent Cholinergic System.Frontiers in neuroscience · 2019Article
- Nicotinic Cholinergic System in the Hypothalamus Modulates the Activity of the Hypothalamic Neuropeptides During the Stress Response.Current neuropharmacology · 2018Review
- Revisiting enigmatic cortical calretinin-expressing interneurons.Frontiers in neuroanatomy · 2014Review
- Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry.EJNMMI research · 2013Article
- Skeletal parasympathetic innervation communicates central IL-1 signals regulating bone mass accrual.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter.Journal of medicinal chemistry · 2010Article
- Intrinsic differences among spatially distinct neural crest stem cells in terms of migratory properties, fate determination, and ability to colonize the enteric nervous system.Developmental biology · 2007Article
- Coexpression of cholinergic and noradrenergic phenotypes in human and nonhuman autonomic nervous system.The Journal of comparative neurology · 2005Article
- Upstream sequencing and functional characterization of the human cholinergic gene locus.Journal of molecular neuroscience : MN · 1997Article
- Vesicular neurotransmitter transporters. Potential sites for the regulation of synaptic function.Molecular neurobiology · 1997Review
- Target-independent cholinergic differentiation in the rat sympathetic nervous system.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Human and monkey cholinergic neurons visualized in paraffin-embedded tissues by immunoreactivity for VAChT, the vesicular acetylcholine transporter.Journal of molecular neuroscience : MN · 1995Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Expression of the acetylcholine biosynthetic enzyme choline acetyltransferase (ChAT), the vesicular acetylcholine transporter (VAChT), and the high-affinity plasma membrane choline transporter uniquely defines the cholinergic phenotype in the mammalian central (CNS) and peripheral (PNS) nervous systems. The distribution of cells expressing the messenger RNA encoding the recently cloned VAChT in the rat CNS and PNS is described here. The pattern of expression of VAChT mRNA is consistent with anatomical, pharmacological, and histochemical information on the distribution of functional cholinergic neurons in the brain and peripheral tissues of the rat. VAChT mRNA-containing cells are present in brain areas, including neocortex and hypothalamus, in which the existence of cholinergic neurons has been the subject of debate. The demonstration that VAChT is a completely adequate marker for cholinergic neurons should allow the systematic delineation of cholinergic synapses in the rat nervous system when antibodies directed to this protein are available.
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