Evidence map›Paper›PMID 7851362›Full record

Trial reportEuropean journal of applied physiology and occupational physiology1994

Enhanced endurance in trained cyclists during moderate intensity exercise following 2 weeks adaptation to a high fat diet.

E V Lambert, D P Speechly, S C Dennis, T D Noakes

Abstract readClinical TrialComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology and occupational physiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Divergent Changes in Peak Fat Oxidation and FatScandinavian journal of medicine & science in sports · 2025
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  8. Trial
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  11. Review
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  13. International society of sports nutrition position stand: ketogenic diets.Journal of the International Society of Sports Nutrition · 2024
    Review
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

E V LambertLiberty Life Chair of Exercise and Sports Science, University of Cape Town Medical School, Observatory, South Africa.
D P Speechly
S C Dennis
T D Noakes

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

These studies investigated the effects of 2 weeks of either a high-fat (HIGH-FAT: 70% fat, 7% CHO) or a high-carbohydrate (HIGH-CHO: 74% CHO, 12% fat) diet on exercise performance in trained cyclists (n = 5) during consecutive periods of cycle exercise including a Wingate test of muscle power, cycle exercise to exhaustion at 85% of peak power output [90% maximal oxygen uptake (VO2max), high-intensity exercise (HIE)] and 50% of peak power output [60% VO2max, moderate intensity exercise (MIE)]. Exercise time to exhaustion during HIE was not significantly different between trials: nor were the rates of muscle glycogen utilization during HIE different between trials, although starting muscle glycogen content was lower [68.1 (SEM 3.9) vs 120.6 (SEM 3.8) mmol.kg-1 wet mass, P < 0.01] after the HIGH-FAT diet. Despite a lower muscle glycogen content at the onset of MIE [32 (SEM 7) vs 73 (SEM 6) mmol.kg-1 wet mass, HIGH-FAT vs HIGH-CHO, P < 0.01], exercise time to exhaustion during subsequent MIE was significantly longer after the HIGH-FAT diet [79.7 (SEM 7.6) vs 42.5 (SEM 6.8) min, HIGH-FAT vs HIGH-CHO, P < 0.01]. Enhanced endurance during MIE after the HIGH-FAT diet was associated with a lower respiratory exchange ratio [0.87 (SEM 0.03) vs (SEM 0.02), P < 0.05], and a decreased rate of carbohydrate oxidation [1.41 (SEM 0.70) vs 2.23 (SEM 0.40) g CHO.min-1, P < 0.05].(ABSTRACT TRUNCATED AT 250 WORDS)

Indexed as

Carbohydrate Metabolism3-Hydroxybutyric AcidAdaptation, PhysiologicalAdultBicyclingBlood Gas AnalysisBlood GlucoseDietary CarbohydratesDietary FatsFatty Acids, NonesterifiedGlycerolGlycogenHumansHydroxybutyratesMaleMuscle, Skeletal3-Hydroxybutyric AcidBlood GlucoseDietary CarbohydratesDietary FatsFatty Acids, NonesterifiedGlycerolGlycogenHydroxybutyrates

Identifiers

PMID7851362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.