ArticleMammalian genome : official journal of the International Mammalian Genome Society1994
Characterization of six new loci within the swine major histocompatibility complex class III region.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Association of multi-pathogenic infections with BAT2, CXCL12, Mx1 and EHMT2 variations in pigs.Molecular biology reports · 2012Article
- Effects of the polymorphisms of Mx1, BAT2 and CXCL12 genes on immunological traits in pigs.Molecular biology reports · 2012Article
- Mapping of the melatonin receptor 1a (MTNR1A) gene in pigs, sheep, and cattle.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Construction of a swine YAC library allowing an efficient recovery of unique and centromeric repeated sequences.Mammalian genome : official journal of the International Mammalian Genome Society · 1997Article
- Swine cytosolic malic enzyme: cDNA cloning, sequencing, and localization.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
- A detailed physical map of the porcine major histocompatibility complex (MHC) class III region: comparison with human and mouse MHC class III regions.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A search for new potential coding sequences was conducted within two overlapping cosmid genomic DNA clusters of about 170 and 45 kb from the swine major histocompatibility complex class III region. The sequences were detected with various probes, including pools of swine cDNA, homologous and heterologous genomic sequences, and synthetic oligonucleotides. The 170 kb cluster was centered on the tumor necrosis factor genes (TNF), and the 45 kb cluster contained the heat-shock protein 70 genes (HSP70). The TNF cluster revealed the presence of five new genes: lymphotoxin beta, BAT1, BAT2, BAT3, and a sequence related to DNA-binding factors. No sequence homologous to B144 was found in the TNF cluster, although other unidentified coding sequences may be present in this cluster. The HSP70 cluster contained a gene identified as BAT6, that is, tRNA-valyl synthetase. These results provide new evidence that the genomic maps of these various genes in the TNF and HSP70 sub-regions are similar in swine and human.
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Registered trials
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