ArticleAmerican journal of human genetics1995
Population genetics of dinucleotide (dC-dA)n.(dG-dT)n polymorphisms in world populations.
Article in American journal of human genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 159 citations in OpenAlex.
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- Leptin gene tetranucleotide repeat polymorphism in obese individuals in Egypt.International journal of health sciences · 2015Article
- Phylogenetic relationship analysis of Iranians and other world populations using allele frequencies at 12 polymorphic markers.Molecular biology reports · 2012Article
- Haplotypic background of a private allele at high frequency in the Americas.Molecular biology and evolution · 2009Article
- Genetic structure in four West African population groups.BMC genetics · 2005Article
- Genetic determinants and ethnic disparities in sepsis-associated acute lung injury.Proceedings of the American Thoracic Society · 2005Review
- Distribution of genome-wide linkage disequilibrium based on microsatellite loci in the Samoan population.Human genomics · 2004Article
- Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms.Genome research · 2003Article
- Features of evolution and expansion of modern humans, inferred from genomewide microsatellite markers.American journal of human genetics · 2003Article
- STRP screening sets for the human genome at 5 cM density.BMC genomics · 2003Article
- An unconditional exact test for the Hardy-Weinberg equilibrium law: sample-space ordering using the Bayes factor.Genetics · 2001Article
- Patterns of ancestral human diversity: an analysis of Alu-insertion and restriction-site polymorphisms.American journal of human genetics · 2001Article
- Reading between the LINEs: human genomic variation induced by LINE-1 retrotransposition.Genome research · 2000Article
- The distribution of human genetic diversity: a comparison of mitochondrial, autosomal, and Y-chromosome data.American journal of human genetics · 2000Article
- Patterns of instability of expanded CAG repeats at the ERDA1 locus in general populations.American journal of human genetics · 1999Article
- Article
- Colorectal adenoma and cancer divergence. Evidence of multilineage progression.The American journal of pathology · 1999Article
- Distribution of haplotypes from a chromosome 21 region distinguishes multiple prehistoric human migrations.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Genetic relationship of populations in China.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
We have characterized eight dinucleotide (dC-dA)n.(dG-dT)n repeat loci located on human chromosome 13q in eight human populations and in a sample of chimpanzees. Even though there is substantial variation in allele frequencies at each locus, at a given locus the most frequent alleles are shared by all human populations. The level of heterozygosity is reduced in isolated or small populations, such as the Pehuenche Indians of Chile, the Dogrib of Canada, and the New Guinea highlanders. On the other hand, larger average heterozygosities are observed in large and cosmopolitan populations, such as the Sokoto population from Nigeria and German Caucasians. Conformity with Hardy-Weinberg equilibrium is generally observed at these loci, unless (a) a population is isolated or small or (b) the repeat motif of the locus is not perfect (e.g., D13S197). Multilocus genotype probabilities at these microsatellite loci do not show departure from the independence rule, unless the loci are closely linked. The allele size distributions at these (CA)n loci do not follow a strict single-step stepwise-mutation model. However, this features does not compromise the ability to detect population affinities, when these loci are used simultaneously. The microsatellite loci examined here are present and, with the exception of the locus D13S197, are polymorphic in the chimpanzees, showing an overlapping distribution of allele sizes with those observed in human populations.
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7847383PMC1801145W2218232968What OpenQuestion holds
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