ReviewNaunyn-Schmiedeberg's archives of pharmacology1994
Complex information processing by the transmembrane signaling system involving G proteins.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 71 citations in OpenAlex.
- A bibliometric study of the most-cited research articles and reviews in Naunyn-Schmiedeberg's Archives of Pharmacology (1969-2024).Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Beyond the wiring diagram: signalling through complex neuromodulator networks.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010Review
- G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype.British journal of pharmacology · 2001Article
- [Genetic polymorphism of the G-protein beta3 subunit, obesity and essential hypertension].Herz · 2000Review
- Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.The Biochemical journal · 1999Article
- Effects of lead on adenylate cyclase activity in rat cerebral cortex.Neurochemical research · 1999Article
- Gsalpha-selective G protein antagonists.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Receptors couple to L-type calcium channels via distinct Go proteins in rat neuroendocrine cell lines.The Journal of physiology · 1997Article
- Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Inhibition of G-protein betagamma-subunit functions by phosducin-like protein.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Crosstalk between thrombin and adenylyl cyclase-stimulating agonists in proliferating human erythroid progenitor cells.Naunyn-Schmiedeberg's archives of pharmacology · 1995Article
- Coupling of an endogenous 5-HT1B-like receptor to increases in intracellular calcium through a pertussis toxin-sensitive mechanism in CHO-K1 cells.British journal of pharmacology · 1995Article
- Differential calcium signalling by m2 and m3 muscarinic acetylcholine receptors in a single cell type.Naunyn-Schmiedeberg's archives of pharmacology · 1995Article
- Subunit composition of G(o) proteins functionally coupling galanin receptors to voltage-gated calcium channels.The EMBO journal · 1995Article
- Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function.Journal of molecular medicine (Berlin, Germany) · 1995Review
- Na+/H+ exchange in hypertension and in diabetes mellitus--facts and hypotheses.Basic research in cardiologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Much of the information cells receive is transduced by a membranous signaling system that uses heterotrimeric guanine nucleotide binding proteins (G proteins) to functionally couple cell surface receptors to a variety of effectors. During recent years it has been shown that receptors, G protein alpha, beta and gamma subunits as well as effectors involved in this signaling system exhibit a remarkable structural diversity and that the interactions of these components display a bewildering complexity. Even though many questions remain to be answered, it is becoming obvious that G proteins form the basis of a complex membranous signaling network which allows the cell to coordinate and to process incoming signals already on the level of the plasma membrane.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.