ArticleActa neuropathologica1994
Primary osteosarcoma of the cerebrum with immunohistochemical and ultrastructural studies: report of a case.
Article in Acta neuropathologica, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Matrix micro/nano-topography drives oncogenic signaling and drug response in a 3D osteosarcoma model.Journal of nanobiotechnology · 2026Article
- Primary Meningeal Extraskeletal Osteosarcoma in a Domestic Shorthaired Cat: Case Report and Review of Comparative Pathology.Veterinary medicine and science · 2026Review
- Primary intracerebral osteosarcoma: a rare case report and review.SpringerPlus · 2016Article
- Primary Hepatic Osteosarcoma: A Rare Cause of Primary Liver Tumor.Clinical medicine insights. Case reports · 2016Article
- Radiation-induced meningeal osteosarcoma of tentorium cerebelli with intradural spinal metastases.Surgical neurology international · 2010Article
- Intracranial osteosarcomas: report of four cases and review of the literature.Journal of neuro-oncology · 1998Review
- Intradural primary chondroblastic osteosarcoma: case report.AJNR. American journal of neuroradiologyArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 57-year-old woman with primary intracerebral osteosarcoma is reported. The tumor was identified by computed tomography as a mass with hemorrhage in the right parietal lobe. The surgical and pathological examinations confirmed an osteosarcoma of intracerebral origin. She suffered from repeated local recurrence of the tumor and died about 1 year after the onset. The pathological findings showed features of osteoblastic osteosarcoma with numerous osteoclast-like multinucleated giant cells. Immunohistochemically, tumor cells were positive for vimentin, and partially for actin. Multinucleated giant cells were reactive with vimentin and CD68 antibodies. Ultrastructurally, tumor cells were rich with rough endoplasmic reticulum. These findings are consistent with the histological features of skeletal or extraskeletal osteosarcoma. This is the third case of primary intracerebral osteosarcoma reported in the literature and the first one analyzed ultrastructurally.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.