Evidence map›Paper›PMID 7829681›Full record

ArticleJournal of clinical pathology1994

Clonal analysis of three morphologically distinct lymphomas occurring in the same patient.

C McCormick, E Philp, J Mansi, N Livni, K McCarthy

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical pathology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 19 citations in OpenAlex.

  1. Expression of PIK3CA and FOXP1 in gastric and intestinal non-Hodgkin's lymphoma of mucosa-associated lymphoid tissue type.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C McCormickDepartment of Histopathology, St George's Hospital Medical School, London.
E Philp
J Mansi
N Livni
K McCarthy
St George's, University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo determine whether three morphologically distinct lymphomas (mucosa associated lymphoid tissue (MALT) lymphoma, monocytoid B cell lymphoma, and large cell anaplastic lymphoma), which occurred in the same patient, were in fact three morphological variants of the same lymphoproliferative process.

methodsPreviously described methods of clonal analysis using the polymerase chain reaction (PCR) were used to determine the pattern of rearrangements of the immunoglobulin heavy chain gene and the T cell receptor beta and T cell receptor gamma chain genes in the three lymphomas.

resultsAll three morphological entities had identical patterns of gene rearrangements.

conclusionsThis finding confirms the association between MALT lymphoma and monocytoid B cell lymphoma, and also provides evidence that large cell anaplastic lymphoma may not only arise de novo but may also be an end stage morphological picture in lymphoma progression.

Indexed as

Gene RearrangementPolymerase Chain ReactionColonic NeoplasmsFemaleGene Rearrangement, beta-Chain T-Cell Antigen ReceptorGene Rearrangement, B-Lymphocyte, Heavy ChainGene Rearrangement, gamma-Chain T-Cell Antigen ReceptorHumansLymphoma, B-CellLymphoma, B-Cell, Marginal ZoneLymphoma, Large-Cell, AnaplasticMiddle AgedNeoplasms, Multiple PrimaryStomach NeoplasmsUterine Cervical Neoplasms

Identifiers

PMID7829681
PMCPMC503070
OpenAlexW1965351415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.