ArticleNucleic acids research1994
Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.
Article in Nucleic acids research, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- HELZ2: a new, interferon-regulated, human 3'-5' exoribonuclease of the RNB family is expressed from a non-canonical initiation codon.Nucleic acids research · 2023Article
- Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.Nucleic acids research · 2015Article
- Proteins associated with SF3a60 in T. brucei.PloS one · 2014Article
- SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles.Molecular biology of the cell · 2012Article
- Structure and assembly of the SF3a splicing factor complex of U2 snRNP.The EMBO journal · 2012Article
- PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.Human molecular genetics · 2011Article
- Interaction domains and nuclear targeting signals in subunits of the U2 small nuclear ribonucleoprotein particle-associated splicing factor SF3a.The Journal of biological chemistry · 2011Article
- U2 snRNP binds intronless histone pre-mRNAs to facilitate U7-snRNP-dependent 3' end formation.Molecular cell · 2007Article
- Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo.Molecular biology of the cell · 2005Article
- Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation.Molecular and cellular biology · 2001Article
- Mutation in the prp12+ gene encoding a homolog of SAP130/SF3b130 causes differential inhibition of pre-mRNA splicing and arrest of cell-cycle progression in Schizosaccharomyces pombe.RNA (New York, N.Y.) · 2001Article
- Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.The EMBO journal · 2000Article
- CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif.Molecular and cellular biology · 1998Article
- Multiple developmental requirements of noisette, the Drosophila homolog of the U2 snRNP-associated polypeptide SP3a60.Molecular and cellular biology · 1998Article
- Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing.Molecular and cellular biology · 1998Article
- In vivo commitment to splicing in yeast involves the nucleotide upstream from the branch site conserved sequence and the Mud2 protein.The EMBO journal · 1997Article
- Functional analysis of the fission yeast Prp4 protein kinase involved in pre-mRNA splicing and isolation of a putative mammalian homologue.Nucleic acids research · 1997Article
- Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations.Genetics · 1996Article
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6 authors.
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Abstract
A cDNA encoding the 60 kDa subunit of mammalian splicing factor SF3a has been isolated. The deduced protein sequence reveals a 30% identity to the PRP9 splicing protein of the yeast S.cerevisiae. The highest homology is present in a zinc finger-like region in the C-terminal domain of both proteins. The PRP9 zinc finger-like motif has been replaced by the equivalent region of mammalian SF3a60. The chimeric protein rescues the temperature-sensitive phenotype of the prp9-1 mutant strain demonstrating that not only the structure but also the function of this domain has been conserved during evolution.
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