ReviewMolecular and cellular biochemistry1994
Calcium and smooth muscle contraction.
Review in Molecular and cellular biochemistry, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 61 citations in OpenAlex.
- High Doses of Caffeine Increase Muscle Strength and Calcium Release in the Plasma of Recreationally Trained Men.Nutrients · 2022Trial
- On the uncertainty quantification of the active uterine contraction during the second stage of labor simulation.Medical & biological engineering & computing · 2024Article
- Perillyl Alcohol Promotes Relaxation in Human Umbilical Artery.Current medicinal chemistry · 2024Article
- Intracellular CaJournal of cardiovascular translational research · 2022Article
- Aqueous Tuber Extracts ofFrontiers in pharmacology · 2021Article
- Major flavonoids fromJournal of advanced research · 2020Article
- A C1976Y missense mutation in the mouse Ip3r1 gene leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles.Experimental animals · 2020Article
- Protease-activated receptor 2 activates CRAC-mediated Ca2+ influx to cause prostate smooth muscle contraction.FASEB bioAdvances · 2019Article
- Genetic Contribution to Variation in Blood Calcium, Phosphorus, and Alkaline Phosphatase Activity in Pigs.Frontiers in genetics · 2019Article
- Effect of metabolic syndrome and aging on CaExperimental gerontology · 2018Article
- Alloxan-induced diabetes exacerbates coronary atherosclerosis and calcification in Ossabaw miniature swine with metabolic syndrome.Journal of translational medicine · 2018Article
- The PPI network analysis of mRNA expression profile of uterus from primary dysmenorrheal rats.Scientific reports · 2018Article
- The regulation of transient receptor potential canonical 4 (TRPC4) channel by phosphodiesterase 5 inhibitor via the cyclic guanosine 3'5'-monophosphate.Pflugers Archiv : European journal of physiology · 2017Article
- Biphasic alterations in coronary smooth muscle Ca(2+) regulation in a repeat cross-sectional study of coronary artery disease severity in metabolic syndrome.Atherosclerosis · 2016Article
- Troponin T3 expression in skeletal and smooth muscle is required for growth and postnatal survival: characterization of Tnnt3(tm2a(KOMP)Wtsi) mice.Genesis (New York, N.Y. : 2000) · 2013Article
- Estimates of marker effects for measures of milk flow in the Italian brown Swiss dairy cattle population.BMC veterinary research · 2012Article
- Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle.Cell motility and the cytoskeleton · 2008Article
- Execution of RIPK3-regulated necrosis.Molecular & cellular oncologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fact that smooth muscle exists in almost every hollow organ and is involved in a large number of disease states has led to a vast increase in smooth muscle research, covering areas from testing response to antagonists and agonists to measuring the molecular force generated by a single actin filament. Yet, the exact mechanisms regulating contractile response of smooth muscle remain unsolved. Calcium has been a central player in mediating smooth muscle contraction through binding with calmodulin, although there is evidence showing that under special circumstances smooth muscle can contract without change in intracellular Ca2+. In addition to the major regulatory pathway of Ca(2+)-calmodulin-myosin light chain kinase, there are other thin filament linked regulatory mechanisms in which Ca(2+)-calmodulin dependent phosphorylation of calponin and caldesmon may be involved. Ca2+ sensitivity of smooth muscle contraction may vary under different situations and this has recently been recognized as an important regulatory mechanism. Examples are protein kinase C (PKC) dependent phosphorylation of myosin light chain kinase which results in partial inhibition of contraction, and activation of myosin light chain phosphatase. There is new evidence showing that not only does Ca2+ regulate contraction by regulating the interaction of contractile proteins in smooth muscle, but also that shortening of smooth muscle itself reduces intracellular Ca2+ concentration, via a negative feedback.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.