ArticleProceedings of the National Academy of Sciences of the United States of America1994
Transcription of histone H4, H3, and H1 cell cycle genes: promoter factor HiNF-D contains CDC2, cyclin A, and an RB-related protein.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 63 citations in OpenAlex.
- The abbreviated pluripotent cell cycle.Journal of cellular physiology · 2013Review
- The architectural organization of human stem cell cycle regulatory machinery.Current pharmaceutical design · 2012Review
- Article
- 3-O-methylfunicone, a metabolite of Penicillium pinophilum, inhibits proliferation of human melanoma cells by causing G(2) + M arrest and inducing apoptosis.Cell proliferation · 2009Article
- Regulation of cell proliferation and differentiation in the kidney.Frontiers in bioscience (Landmark edition) · 2009Review
- c-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression.Molecular and cellular biology · 2007Article
- Human replication-dependent histone H3 genes are activated by a tandemly arranged pair of two CCAAT boxes.The Biochemical journal · 2004Article
- Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase.Molecular and cellular biology · 2003Article
- Optimized chimeras between kinase-inactive mutant Cdk9 and truncated cyclin T1 proteins efficiently inhibit Tat transactivation and human immunodeficiency virus gene expression.Journal of virology · 2002Article
- Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility.Molecular and cellular biology · 2002Article
- Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription.The EMBO journal · 2001Article
- The maternal effect gene, abnormal oocyte (abo), of Drosophila melanogaster encodes a specific negative regulator of histones.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression.Molecular and cellular biology · 2000Article
- Multilevel regulation of histone gene expression during the cell cycle in tobacco cells.Nucleic acids research · 1998Article
- Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency.Molecular and cellular biology · 1997Article
- CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Identification of a second conserved element within the coding sequence of a mouse H3 histone gene that interacts with nuclear factors and is necessary for normal expression.Nucleic acids research · 1996Article
- Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation.The Iowa orthopaedic journal · 1995Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Cell cycle-controlled human histone genes are coordinately expressed during S phase, and transcriptional regulation involves a series of trans-acting factors (HiNFs). The proliferation-specific factor HiNF-D interacts with multiple recognition motifs in histone H4, H3, and H1 promoters. Using gel shift immunoassays, we show that CDC2, cyclin A, and an RB-related protein are ubiquitous subunits of HiNF-D binding activity isolated from several cell types. HiNF-D levels in vivo are sensitive to okadaic acid and staurosporine, indicating that HiNF-D activity and/or assembly is influenced by phosphorylation status. Thus, HiNF-D appears to be a multicomponent phosphoprotein that participates in coordinate control of multiple histone H4, H3, and H1 genes during the cell cycle. The presence of cell cycle mediators in the HiNF-D complex suggests linkage between transcriptional control of histones, enzymes involved in DNA synthesis, and the onset of DNA replication during the G1/S phase transition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.