ReviewMolecular and cellular biochemistry
Compartmentation of ATP synthesis and utilization in smooth muscle: roles of aerobic glycolysis and creatine kinase.
Review in Molecular and cellular biochemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 60 citations in OpenAlex.
- Aerobic metabolism on muscle contraction in porcine gastric smooth muscle.The Journal of veterinary medical science · 2018Article
- Phloridzin inhibits high KThe Journal of veterinary medical science · 2017Article
- Metabolic Stress-Induced Activation of AMPK and Inhibition of Constitutive Phosphoproteins Controlling Smooth Muscle Contraction: Evidence for Smooth Muscle Fatigue?Frontiers in physiology · 2017Article
- Aerobic metabolism on muscle contraction in porcine iris sphincter.The Journal of veterinary medical science · 2016Article
- Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca(2+) regulation in airway smooth muscle (ASM).Canadian journal of physiology and pharmacology · 2015Review
- Hypoxic pulmonary vasoconstriction.Physiological reviews · 2012Review
- Metabolic compartmentation - a system level property of muscle cells: real problems of diffusion in living cells.International journal of molecular sciences · 2008Article
- The function of mitochondria in presynaptic development at the neuromuscular junction.Molecular biology of the cell · 2008Article
- Defective metabolic signaling in adenylate kinase AK1 gene knock-out hearts compromises post-ischemic coronary reflow.The Journal of biological chemistry · 2007Article
- Local PIP(2) signals: when, where, and how?Pflugers Archiv : European journal of physiology · 2007Review
- Aging perturbs 26S proteasome assembly in Drosophila melanogaster.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2007Article
- Presence of normal creatine in the muscle of a patient with a mutation in the creatine transporter: a case study.Molecular and cellular biochemistry · 2004Article
- Origin of ATP for Ca2+-induced contraction in the guinea-pig femoral artery.Naunyn-Schmiedeberg's archives of pharmacology · 2004Article
- New insights into the bioenergetics of mitochondrial disorders using intracellular ATP reporters.Molecular biology of the cell · 2003Article
- Endothelium and smooth muscle of pig coronary artery: differences in metabolism.Molecular and cellular biochemistry · 2003Article
- Functional coupling of creatine kinases in muscles: species and tissue specificity.Molecular and cellular biochemistry · 1998Article
- Oxidative phosphorylation in myocardial mitochondria 'in situ': a calorimetric study on permeabilized cardiac muscle preparations.Molecular and cellular biochemistry · 1997Article
- Energetic cost of activation processes during contraction of swine arterial smooth muscle.The Journal of physiology · 1997Article
- Mitochondrial DNA mutations and pathogenesis.Journal of bioenergetics and biomembranes · 1997Review
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Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The phosphocreatine content of smooth muscle is of similar magnitude to ATP. Thus the function of the creatine kinase system in this tissue cannot simply be regarded as an energy buffer. Thus an understanding of its role in smooth muscle behavior can point to CK function in other systems. From our perspective CK function in smooth muscle is one example of a more general phenomenon, that of the co-localization of ATP synthesis and utilization. In an interesting and analogous fashion distinct glycolytic cascades are also localized in regions of the cell with specialized energy requirements. Similar to CK, glycolytic enzymes are known to be localized on thin filaments, sarcoplasmic reticulum and plasma membrane. In this chapter we will describe the relations between glycolysis and smooth muscle function and compare and contrast to that of the CK system. Our goal is to more fully understand the significance of the compartmentation of distinct pathways for ATP synthesis with specific functions in smooth muscle. This organization of metabolism and function seen most clearly in smooth muscle is likely representative of many other cell types.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.