ReviewMolecular and cellular biochemistry
Myofibrillar creatine kinase and cardiac contraction.
Review in Molecular and cellular biochemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 114 citations in OpenAlex.
- Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy.Circulation. Heart failure · 2022Article
- MuRF1/TRIM63, Master Regulator of Muscle Mass.International journal of molecular sciences · 2020Review
- Cardiac Resynchronisation Therapy and Cellular Bioenergetics: Effects Beyond Chamber Mechanics.European cardiology · 2019Review
- A comprehensive review of the bioenergetics of fatty acid and glucose metabolism in the healthy and failing heart in nondiabetic condition.Heart failure reviews · 2017Review
- A step toward systems metabolomics.Physiological genomics · 2012Article
- Redox proteomics identification of oxidatively modified myocardial proteins in human heart failure: implications for protein function.PloS one · 2012Article
- Cardiac muscle ring finger-1--friend or foe?Trends in cardiovascular medicine · 2010Review
- Low creatine kinase is associated with a high population incidence of fainting.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2009Article
- Oxidative modification and aggregation of creatine kinase from aged mouse skeletal muscle.Aging · 2009Article
- Metabolic compartmentation - a system level property of muscle cells: real problems of diffusion in living cells.International journal of molecular sciences · 2008Article
- Creatine kinase binds more firmly to the M-band of rabbit skeletal muscle myofibrils in the presence of its substrates.Molecular and cellular biochemistry · 2007Article
- Orchestration of lymphocyte chemotaxis by mitochondrial dynamics.The Journal of experimental medicine · 2006Article
- Heart failure: a model of cardiac and skeletal muscle energetic failure.Pflugers Archiv : European journal of physiology · 2006Review
- Effect of ADP on slow-twitch muscle fibres of the rat: implications for muscle fatigue.The Journal of physiology · 2006Article
- Interaction between signalling pathways involved in skeletal muscle responses to endurance exercise.Pflugers Archiv : European journal of physiology · 2006Review
- Impaired voluntary running capacity of creatine kinase-deficient mice.The Journal of physiology · 2005Article
- Intracellular energetic units in healthy and diseased hearts.Experimental and clinical cardiology · 2005Article
- Effects of ADP on action potential-induced force responses in mechanically skinned rat fast-twitch fibres.The Journal of physiology · 2004Article
- Energy metabolism in heart failure.The Journal of physiology · 2004Review
- Heterogeneity of ADP diffusion and regulation of respiration in cardiac cells.Biophysical journal · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article is a review on the organization and function of myofibrillar creatine kinase in striated muscle. The first part describes myofibrillar creatine kinase as an integral structural part of the complex organization of myofibrils in striated muscle. The second part considers the intrinsic biochemical and mechanical properties of myofibrils and the functional coupling between myofibrillar CK and myosin ATPase. Skinned fiber studies have been developed to evidence this functional coupling and the consequences for cardiac contraction. The data show that creatine kinase in myofibrils is effective enough to sustain normal tension and relaxation, normal Ca sensitivity and kinetic characteristics. Moreover, the results suggest that myofibrillar creatine kinase is essential in maintaining adequate ATP/ADP ratio in the vicinity of myosin ATPase active site to prevent dysfunctioning of this enzyme. Implications for the physiology and physiopathology of cardiac muscle are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.