ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology1994
Aspergillus antigenuria compared to antigenemia in bone marrow transplant recipients.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 56 citations in OpenAlex.
- Aspergillus antigen testing in bone marrow transplant recipients.Journal of clinical pathology · 2000Trial
- Real-Time Single-Aggregate Analysis of Vaccine Antigen Stability via Stochastic Electrochemical Blocking.The AAPS journal · 2026Article
- Article
- Detection of urinary excreted fungal galactomannan-like antigens for diagnosis of invasive aspergillosis.PloS one · 2012Article
- Update on the contribution of galactomannan for the diagnosis of invasive aspergillosis.Mycopathologia · 2007Review
- Current status of nonculture methods for diagnosis of invasive fungal infections.Clinical microbiology reviews · 2002Review
- Comparison of commercial latex agglutination and sandwich enzyme immunoassays with a competitive binding inhibition enzyme immunoassay for detection of antigenemia and antigenuria in a rabbit model of invasive aspergillosis.Clinical and diagnostic laboratory immunology · 2000Article
- Aspergillus Fumigatus antigen detection in sera from patients at risk for invasive aspergillosis.Journal of clinical microbiology · 2000Article
- A polymerase chain reaction enzyme immunoassay for diagnosing infection caused by Aspergillus fumigatus.Journal of clinical pathology · 1999Article
- Aspergillus fumigatus and aspergillosis.Clinical microbiology reviews · 1999Review
- Comparison of an enzyme immunoassay and latex agglutination test for detection of galactomannan in the diagnosis of invasive aspergillosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1996Article
- Comparison of antigen detection and PCR assay using bronchoalveolar lavage fluid for diagnosing invasive pulmonary aspergillosis in patients receiving treatment for hematological malignancies.Journal of clinical microbiology · 1995Article
- Sandwich enzyme-linked immunosorbent assay compared with Pastorex latex agglutination test for diagnosing invasive aspergillosis in immunocompromised patients.Journal of clinical microbiology · 1995Article
- Clinical evaluation and reproducibility of the Pastorex Aspergillus antigen latex agglutination test for diagnosing invasive aspergillosis.Journal of clinical pathology · 1995Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The detection of galactomannan antigen in urine was investigated in 26 bone marrow transplant recipients using an Aspergillus latex agglutination test (Pastorex). After modification of the method, which was originally devised for serum testing, the detection limit in native urine was approximately 20 ng/ml. Antigen was found in 79 (36.4%) of 217 serial urine samples, compared to 40 (11.8%) of 340 serum samples. As a rule, antigenuria preceded antigenemia and was more persistent. The sensitivity, specificity, positive predictive value and negative predictive value of antigenuria for autopsy-proven aspergillosis and clinically suspected Aspergillus infection were 57%, 53%, 31% and 77%, respectively, while those of antigenemia were 43%, 53%, 25% and 71%. It is concluded that urine testing is more reliable than serum testing for the detection of Aspergillus galactomannan. The detection of antigen, however, whether in serum or in urine, allows no clear distinction between Aspergillus infection and exposure to non-infectious Aspergillus antigens.
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