Evidence map›Paper›PMID 7795410›Full record

ArticleGlycoconjugate journal1995

Lectins and also bacteria modify the glycosylation of gut surface receptors in the rat.

A Pusztai, S W Ewen, G Grant, W J Peumans, E J Van Damme, M E Coates, S Bardocz

Abstract read
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In one paragraph

Article in Glycoconjugate journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 77 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

A PusztaiRowett Research Institute, Bucksburn, Aberdeen, UK.
S W Ewen
G Grant
W J Peumans
E J Van Damme
M E Coates
S Bardocz
KU Leuven · BEUniversity of Aberdeen · GBUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral exposure to lectins or the presence or absence of bacteria in the rat small intestine were shown by histological methods using anti-lectin antibodies or digoxigenin-labelled lectins to have major effects on the state of glycosylation of lumenal membranes and cytoplasmic glycoconjugates of epithelial cells. Taken together with the dramatic effects of exposure to lectins on gut function, metabolism and bacterial ecology, this can be used as a basis for new perspectives of biomedical manipulations to improve health.

Indexed as

Bacterial Physiological PhenomenaAdministration, OralAgglutininsAnimal Nutritional Physiological PhenomenaAnimalsAntibodiesAntigens, SurfaceCarbohydrate SequenceConcanavalin ADigoxigeninFucoseGerm-Free LifeGlycosylationIntestinal MucosaIntestinesIntestine, SmallAgglutininsAntibodiesAntigens, SurfaceConcanavalin ADigoxigeninFucoseLectinsMembrane Glycoproteins

Identifiers

PMID7795410
OpenAlexW2038809658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.