Evidence map›Paper›PMID 7790091›Full record

ArticleInfection and immunity1995

iactA of Listeria ivanovii, although distantly related to Listeria monocytogenes actA, restores actin tail formation in an L. monocytogenes actA mutant.

E Gouin, P Dehoux, J Mengaud, C Kocks, P Cossart

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Infection and immunity, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
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  13. Actin-dependent movement of bacterial pathogens.Nature reviews. Microbiology · 2006
    Review
  14. Article
  15. Article
  16. Article
  17. Actin-based motility of intracellular microbial pathogens.Microbiology and molecular biology reviews : MMBR · 2001
    Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

E GouinUnité des Interactions Bactéries-Cellules, Institut Pasteur, Paris, France.
P Dehoux
J Mengaud
C Kocks
P Cossart
Institut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A gene homologous to the actA gene of Listeria monocytogenes was cloned from Listeria ivanovii (strain CLIP257) by chromosome walking starting from the ilo gene that encodes the pore-forming toxin ivanolysin. The nucleotide sequence revealed that this gene, named iactA, encodes a protein of 1,044 amino acids (IactA) comprising a central region with seven highly conserved tandem proline-rich repeats of 47 amino acids. Although IactA and ActA share an overall similar structure, these two proteins are only distantly related. Like ActA, IactA migrates aberrantly on sodium dodecyl sulfate gels. When expressed in an L. monocytogenes actA deletion mutant strain, iactA restored actin polymerization.

Indexed as

Genes, BacterialActinsAmino Acid SequenceAnimalsBacterial ProteinsBase SequenceBlotting, WesternChlorocebus aethiopsDNA, BacterialDNA PrimersGenetic Complementation TestListeriaListeria monocytogenesListeriosisMembrane ProteinsMolecular Sequence DataactA protein, Listeria monocytogenesActinsBacterial ProteinsDNA, BacterialDNA PrimersMembrane Proteins

Identifiers

PMID7790091
PMCPMC173365
OpenAlexW2160289657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.