ArticleBiophysical journal1995
Analysis of high resolution recordings of motor movement.
Article in Biophysical journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed.
- Direct observation of processive exoribonuclease motion using optical tweezers.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Kinesin walks the line: single motors observed by atomic force microscopy.Biophysical journal · 2011Article
- In vitro assays to study the tracking of shortening microtubule ends and to measure associated forces.Methods in cell biology · 2010Review
- Article
- Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Kinesin steps do not alternate in size.Biophysical journal · 2008Article
- Kinesin motor mechanics: binding, stepping, tracking, gating, and limping.Biophysical journal · 2007Review
- Article
- Hidden-Markov methods for the analysis of single-molecule actomyosin displacement data: the variance-Hidden-Markov method.Biophysical journal · 2001Article
- Quantal sarcomere-length changes in relaxed single myofibrils.Biophysical journal · 2001Article
- Direct tests of muscle cross-bridge theories: predictions of a Brownian dumbbell model for position-dependent cross-bridge lifetimes and step sizes with an optically trapped actin filament.Biophysical journal · 1998Article
- Mechanics of single kinesin molecules measured by optical trapping nanometry.Biophysical journal · 1997Article
- Kinetics of force generation by single kinesin molecules activated by laser photolysis of caged ATP.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap.Biophysical journal · 1997Article
- New insights into the workings of the ultimate swimming machine.Biophysical journal · 1996Article
- Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Preparation of bead-tailed actin filaments: estimation of the torque produced by the sliding force in an in vitro motility assay.Biophysical journal · 1996Article
- Structural and functional features of one- and two-headed biotinated kinesin derivatives.Biophysical journal · 1995Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of in vitro motility assays for motor proteins has been accompanied by a parallel development of advanced optical instrumentation capable of recording motion at the molecular level. Devices now exist that can record displacements to better than 0.1 nm at bandwidths in excess of 10 kHz, and that can place controlled forces up to many pN on single motors. Ultra-high resolution data from experiments are now pouring in. The analysis and subsequent interpretation of experimental records, which are inevitably contaminated with high levels of thermal noise, remain an ongoing challenge. This essay examines selected issues relating to this challenge and discusses some alternative approaches.
Indexed as
Identifiers
7787083PMC1281932What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.