ArticleBiophysical journal1995
Molecular genetic analysis of myoF, a new Dictyostelium myosin I gene.
Article in Biophysical journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Selective localization of myosin-I proteins in macropinosomes and actin waves.Cytoskeleton (Hoboken, N.J.) · 2016Article
- Crystal structure of the motor domain of a class-I myosin.The EMBO journal · 2002Article
- Myosin I overexpression impairs cell migration.The Journal of cell biology · 1997Article
- Dictyostelium discoideum myoJ: a member of a broadly defined myosin V class or a class XI unconventional myosin?Journal of muscle research and cell motility · 1996Article
- Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis.The Journal of cell biology · 1995Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several new members of the Dictyostelium myosin family have been identified by physical mapping techniques in combination with PCR. Here we describe the initial molecular genetic characterization of one of these, myoF. A 1-kb segment of the myoF gene was obtained by the PCR and used as a specific probe for Northern analysis and as a vehicle for gene-targeting studies. The myoF gene is expressed as a 3.7-kb message, a size consistent with it encoding a myosin I class unconventional myosin, bringing the total of myosin is present in Dictyostelium to six. Analysis of strains in which the myoF gene has been disrupted reveals that loss of the myoF protein does not result in obvious defects either in cellular translocation, or in other readily assayed actin-based processes. The results of our investigation indicate that the myosin I family is quite large in Dictyostelium, and that several members, including myoF, may either be functionally redundant or play roles in as yet undescribed actin-based processes.
Indexed as
Identifiers
7787058PMC1281899What OpenQuestion holds
Registered trials
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