ArticleBMJ (Clinical research ed.)1995
Ten year cerebrovascular morbidity and mortality in 68 year old men with asymptomatic carotid stenosis.
Article in BMJ (Clinical research ed.), 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 72 citations in OpenAlex.
- Article
- Influence of Dietary Patterns and Inflammatory Markers on Atherosclerosis Using Ankle Brachial Index as a Surrogate.The journal of nutrition, health & aging · 2018Article
- Depressive symptoms, atherosclerotic burden and cerebral blood flow disturbances in a cohort of octogenarian men from a general population.BMC psychiatry · 2013Article
- Peripheral arterial disease in the Middle East: Underestimated predictor of worse outcome.Global cardiology science & practice · 2013Review
- Carotid velocities determine cerebral blood flow deficits in elderly men with carotid stenosis <50%.International journal of vascular medicine · 2012Article
- Differing pattern of ambulatory blood pressure in very elderly men expresses dynamics in atherosclerotic load in the senescence.International journal of hypertension · 2012Article
- Peripheral Arterial Disease study (PERART): prevalence and predictive values of asymptomatic peripheral arterial occlusive disease related to cardiovascular morbidity and mortality.BMC public health · 2007Article
- Clinically relevant depressive symptoms and peripheral arterial disease in elderly men and women. Results from a large cohort study in Southern China.Journal of psychosomatic research · 2007Article
- Systemic risk score evaluation in ischemic stroke patients (SCALA): a prospective cross sectional study in 85 German stroke units.Journal of neurology · 2007Article
- Bone mineral density and the risk of peripheral arterial disease in men and women: results from Mr. and Ms Os, Hong Kong.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2005Article
- Adaptive behavior in stressful situations in relation to postinfarction mortality results from prospective cohort study "Men Born in 1914" in Malmo, Sweden.International journal of behavioral medicine · 2003Article
- Comparison of different procedures to identify probable cases of myocardial infarction and stroke in two Swedish prospective cohort studies using local and national routine registers.European journal of epidemiology · 2000Article
- A surgical approach to coexistent coronary and carotid artery disease.Heart (British Cardiac Society) · 1997Article
- Use of ankle brachial pressure index to predict cardiovascular events and death: a cohort study.BMJ (Clinical research ed.) · 1996Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the natural course of carotid artery stenosis detected by ultrasonography.
designProspective cohort study. Baseline examination in 1982-3 included ultrasound examination of carotid arteries, measurement of ankle-brachial blood pressure index, and detection of atrial fibrillation by 24 hour ambulatory electrocardiography.
settingMalmö, a city in southern Sweden with 230,000 inhabitants. SUBJECTS: 470 men aged 68 years randomly selected from the population.
main outcome measuresIncidence of stroke and transient ischaemic attack and all cause mortality during 10 years of follow up in relation to carotid stenosis, leg artery disease (ankle-brachial blood pressure index below 0.9), and atrial fibrillation.
resultsFifty men had a stroke; six of these were haemorrhagic. Another 11 had a transient ischaemic attack. Eighteen of the men with carotid stenosis (21.6 events/1000 person years) and 43 of the men with normal carotid arteries (14.8 events/1000 person years) had a stroke or transient ischaemic attack (P = 0.188). Men with atrial fibrillation had an increased rate of cerebrovascular events (36.7/1000 person years (P = 0.048). The highest rate was found in men with asymptomatic disease of the leg arteries (38.6/1000 person years) (P < 0.001). The increased risk of stroke or transient ischaemic attack in this group remained after multivariate analysis (relative risk 2.0; 95% confidence interval 1.1 to 3.7).
conclusionsIn this cohort carotid stenosis was not associated with an increased risk of stroke. Part of this lack of association was explained by the high mortality from ischaemic heart disease in men with severe stenosis. Twenty seven of the 61 cerebrovascular events, however, occurred in men who had normal carotid arteries, normal ankle pressure, and no atrial fibrillation.
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