ArticleGenetics1995
Promoter elements in Drosophila melanogaster revealed by sequence analysis.
Article in Genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed.
- Quantitative analysis of transcription start site selection reveals control by DNA sequence, RNA polymerase II activity and NTP levels.Nature structural & molecular biology · 2024Article
- Tandem duplications lead to novel expression patterns through exon shuffling in Drosophila yakuba.PLoS genetics · 2017Article
- The ABCs of eye color in Tribolium castaneum: orthologs of the Drosophila white, scarlet, and brown Genes.Genetics · 2015Article
- Transcriptional properties and splicing of the flamenco piRNA cluster.EMBO reports · 2014Article
- Plant promoters: an approach of structure and function.Molecular biotechnology · 2014Review
- Transcriptional activity of the FUT1 gene promoter region in pigs.International journal of molecular sciences · 2013Article
- Drosophila nuclear factor DREF regulates the expression of the mitochondrial DNA helicase and mitochondrial transcription factor B2 but not the mitochondrial translation factor B1.Biochimica et biophysica acta · 2013Article
- High-resolution characterization of Toxoplasma gondii transcriptome with a massive parallel sequencing method.DNA research : an international journal for rapid publication of reports on genes and genomes · 2010Article
- A subtelomeric non-LTR retrotransposon Hebe in the bdelloid rotifer Adineta vaga is subject to inactivation by deletions but not 5' truncations.Mobile DNA · 2010Article
- Transcriptional regulation of mammalian selenoprotein expression.Biochimica et biophysica acta · 2009Review
- POIMs: positional oligomer importance matrices--understanding support vector machine-based signal detectors.Bioinformatics (Oxford, England) · 2008Article
- Article
- Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequilibrium in eukaryote genomes using frequency distribution curves.BMC bioinformatics · 2006Article
- Identification of multiple transcription initiation, polyadenylation, and splice sites in the Drosophila melanogaster TART family of telomeric retrotransposons.Nucleic acids research · 2006Article
- Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola.Genes & development · 2003Article
- Promoter competition as a mechanism of transcriptional interference mediated by retrotransposons.The EMBO journal · 2002Article
- The Drosophila suppressor of underreplication protein binds to late-replicating regions of polytene chromosomes.Genetics · 2002Article
- Coupling of enhancer and insulator properties identified in two retrotransposons modulates their mutagenic impact on nearby genes.Molecular and cellular biology · 2002Article
- Computational analysis of core promoters in the Drosophila genome.Genome biology · 2002Article
- Functional regulation of glutamine:fructose-6-phosphate aminotransferase 1 (GFAT1) of Drosophila melanogaster in a UDP-N-acetylglucosamine and cAMP-dependent manner.The Biochemical journal · 2001Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
A Drosophila Promoter Database containing 252 independent Drosophila melanogaster promoter entries has been compiled. The database and its subsets have been searched for overrepresented sequences. The analysis reveals that the proximal promoter region displays the most dramatic nucleotide sequence irregularities and exhibits a tripartite structure, consisting of TATA at -25/-30 bp, initiator (Inr) at +/- 5 bp and a novel class of downstream elements at +20/+30 bp from the RNA start site. These latter elements are also strand-specific. However, they differ from TATA and Inr in several aspects: (1) they are represented not by a single, but by multiple sequences, (2) they are shorter, (3) their position is less strictly fixed with respect to the RNA start site, (4) they emerge as a characteristic feature of Drosophila promoters and (5) some of them are strongly overrepresented in the TATA-less, but not TATA-containing, subset. About one-half of known Drosophila promoters can be classified as TATA-less. The overall sequence organization of the promoter region is characterized by an extended region with an increase in GC-content and a decrease in A, which contains a number of binding sites for Drosophila transcription factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.