ArticleMammalian genome : official journal of the International Mammalian Genome Society1995
Mapping of the focal adhesion kinase (Fadk) gene to mouse chromosome 15 and human chromosome 8.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- The Crosstalk between FAK and Wnt Signaling Pathways in Cancer and Its Therapeutic Implication.International journal of molecular sciences · 2020Review
- Male germline recombination of a conditional allele by the widely used Dermo1-cre (Twist2-cre) transgene.Genesis (New York, N.Y. : 2000) · 2017Article
- Regulation of FAK Activity by Tetraspan Proteins: Potential Clinical Implications in Cancer.Critical reviews in oncogenesis · 2015Review
- Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer.Cancer letters · 2014Article
- New insights into FAK function and regulation during spermatogenesis.Histology and histopathology · 2014Review
- Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions.Microvascular research · 2012Review
- Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis.Advanced drug delivery reviews · 2011Review
- Focal adhesion kinase and p53 signal transduction pathways in cancer.Frontiers in bioscience (Landmark edition) · 2010Review
- Neurofibromin physically interacts with the N-terminal domain of focal adhesion kinase.Molecular carcinogenesis · 2009Article
- A second generation radiation hybrid map to aid the assembly of the bovine genome sequence.BMC genomics · 2006Article
- Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.Oncogene · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Focal adhesion kinase (pp125FAK or FAK) is a cytoplasmic protein-tyrosine kinase stimulated in response to cell interactions with extracellular matrix components and by exposure to a variety of agonists, including neuropeptides. FAK lacks Src-homology SH2 and SH3 domains, is highly conserved across species, and may represent the prototype for a tyrosine kinase family involved in novel signal transduction pathways. We have identified sequence variants in the 3' untranslated regions of the focal adhesion kinase gene in mice and used a PCR-based oligonucleotide hybridization assay to map the mouse gene (Fadk) to Chromosome (Chr) 15 distal to the myelocytomatosis protooncogene (Myc). The human homolog (PTK2) has been assigned to human Chr 8 on a panel of somatic hybrid cell lines. On the basis of synteny of mouse and human chromosomal maps, the position of the human PTK2 gene probably corresponds to human Chr 8q24-qter.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.