Evidence map›Paper›PMID 7765092›Full record

ArticleCurrent microbiology1994

Identification of three chitin synthase genes in the dimorphic fungal pathogen Sporothrix schenckii.

S S Chua, M Momany, L Mendoza, P J Szaniszlo

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 25 citations in OpenAlex.

  1. Sporothrix schenckii and Sporotrichosis.Clinical microbiology reviews · 2011
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

S S ChuaDepartment of Microbiology, University of Texas at Austin 78712-1095.
M Momany
L Mendoza
P J Szaniszlo
The University of Texas at Austin · US

Funding

WANGIELLA MODEL FOR DEMATIACEOUS FUNGAL PATHOGENSR01AI033049 · NIAID · UNIVERSITY OF TEXAS AUSTIN · PI SZANISZLO, PAUL J · 1993 to 2007
$1.8M
NIAID NIH HHS AI 33049
6 · The paper itself

Abstract

Degenerate PCR primers were used to amplify a 600-bp conserved gene region for chitin synthases from genomic DNA of Sporothrix schenckii, a dimorphic fungal pathogen of humans and animals. Three chitin synthase gene homologs were amplified as shown by DNA sequence analysis and by Southern blotting experiments. Based on differences among the predicted amino acid sequences of these homologs, each was placed within one of three different chitin synthase classes. Phylogenies constructed with the sequences and the PAUP 3.1.1 program showed that S. schenckii consistently clustered most closely with Neurospora crassa in each of the three chitin synthase classes. These findings are significant because the phylogenies support by a new method the grouping of the imperfect fungus S. schenckii with the Pyrenomycetes of the Ascomycota.

Indexed as

Genes, FungalBase SequenceBlotting, SouthernChitin SynthaseDNA, FungalMolecular Sequence DataPhylogenyPolymerase Chain ReactionSequence Analysis, DNASporothrixChitin SynthaseDNA, Fungal

Identifiers

PMID7765092
OpenAlexW1965983809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.