Evidence map›Paper›PMID 7761468›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1995

Ordered restriction endonuclease maps of yeast artificial chromosomes created by optical mapping on surfaces.

W Cai, H Aburatani, V P Stanton, D E Housman, Y K Wang, D C Schwartz

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Advances in optical mapping for genomic research.Computational and structural biotechnology journal · 2020
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Overview of Next-Generation Sequencing Technologies.Current protocols in molecular biology · 2018
    Review
  9. Article
  10. Methyltransferase-Directed Labeling of Biomolecules and its Applications.Angewandte Chemie (International ed. in English) · 2017
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

W CaiW. M. Keck Laboratory for Biomolecular Imaging, Department of Chemistry, New York University, NY 10003, USA.
H Aburatani
V P Stanton
D E Housman
Y K Wang
D C Schwartz

Funding

NEW PHYSICAL METHODOLOGIES FOR GENOMIC ANALYSISR01HG000225 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI SCHWARTZ, DAVID C. · 1991 to 2014
$5.2M
STUDY OF THE FIBRONECTIN FUNCTIONP01HL041484 · NHLBI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KRIEGER, MONTY · 1988 to 2000
$2.7M
HIGH THROUGHPUT LOW COST IRS-PCR BASED GENOTYPINGR01HG000299 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HOUSMAN, DAVID E · 1990 to 2001
$1.1M
NHGRI NIH HHS HG00225-02NHGRI NIH HHS HG00299NHLBI NIH HHS HL41484
6 · The paper itself

Abstract

We have developed a surface mounting technology for the rapid construction of ordered restriction maps from individual DNA molecules. Optical restriction maps constructed from yeast artificial chromosome DNA molecules mounted on specially derivatized glass surfaces are accurate and reproducible, and the technology is amenable to automation. The mounting procedures described here should also be useful for fluorescence in situ hybridization studies. We believe these improvements to optical mapping will further stimulate the development of nonelectrophoretic approaches to genome analysis.

Indexed as

Chromosomes, Artificial, YeastRestriction MappingAutomationDNA, FungalMicroscopy, FluorescenceMolecular WeightSaccharomyces cerevisiaeDNA, Fungal

Identifiers

PMID7761468
PMCPMC41869

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.