ReviewThe Journal of experimental medicine1995
Ceramide: a signal for apoptosis or mitogenesis?
Review in The Journal of experimental medicine, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Lipotoxicity: A New Perspective in Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Is there a potential of circulating miRNAs as biomarkers in rheumatic diseases?Genes & diseases · 2023Review
- Ceramide signals for initiation of yeast mating-specific cell cycle arrest.Cell cycle (Georgetown, Tex.) · 2016Article
- Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL.Redox biology · 2015Article
- Article
- Quantitation of ceramide phosphorylethanolamines containing saturated and unsaturated sphingoid base cores.Analytical biochemistry · 2010Article
- Enhanced detection of sphingoid bases via divalent ruthenium bipyridine complex derivatization and electrospray ionization tandem mass spectrometry.Analytical chemistry · 2009Article
- Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I.The Journal of experimental medicine · 1999Article
- Signal transduction of stress via ceramide.The Biochemical journal · 1998Review
- Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells.Annals of the rheumatic diseases · 1998Article
- Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival.The Journal of cell biology · 1998Article
- Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin.Infection and immunity · 1998Article
- Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells.The Journal of experimental medicine · 1998Article
- Synovial fibroblasts and the sphingomyelinase pathway: sphingomyelin turnover and ceramide generation are not signaling mechanisms for the actions of tumor necrosis factor-alpha.The American journal of pathology · 1998Article
- SARPs: a family of secreted apoptosis-related proteins.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion.The American journal of pathology · 1997Article
- Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis.The EMBO journal · 1997Article
- Ceramide inhibits antigen uptake and presentation by dendritic cells.The Journal of experimental medicine · 1996Article
- Role of protein kinase activity in apoptosis.Experientia · 1996Review
- CD28: a signalling perspective.The Biochemical journal · 1996Review
Corrections and comments
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Authors and funding
2 authors.
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Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.