Evidence map›Paper›PMID 7751316›Full record

ArticleJournal of bacteriology1995

The "universal" leucine codon CTG in the secreted aspartyl proteinase 1 (SAP1) gene of Candida albicans encodes a serine in vivo.

T C White, L E Andrews, D Maltby, N Agabian

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. A Bright Future for Fluorescence Imaging of Fungi in Living Hosts.Journal of fungi (Basel, Switzerland) · 2019
    Review
  2. Article
  3. Article
  4. Review
  5. Reporters for the analysis of N-glycosylation in Candida albicans.Fungal genetics and biology : FG & B · 2013
    Article
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

T C WhiteDepartment of Stomatology, University of California-San Francisco, USA.
L E Andrews
D Maltby
N Agabian
University of California, San Francisco · US

Funding

ORAL MANIFESTATIONS OF THE ACQUIRED IMMUNODEFICIENCY SP01DE007946 · NIDCR · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI HILTON, JOAN F · 1987 to 2004
$5.8M
ORAL CANDIDIASIS IN LENTIVIRUS INFECTED MACAQUESR01DE011367 · NIDCR · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI WHITE, THEODORE C. · 1994 to 2007
$2.5M
AIDS-RELATED CANDIDIASIS--THE ROLE OF ACID PROTEASESR01AI033317 · NIAID · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI AGABIAN, NINA · 1992 to 2000
$252k
NIAID NIH HHS 1RO1AI-33317NIDCR NIH HHS 1RO1DE11367NIDCR NIH HHS P01-DE-07946
6 · The paper itself

Abstract

A number of Candida species possess a tRNA(Ser)-like species that recognizes CTG codons that normally specify leucine (Leu) in the universal code of codon usage. Mass spectrometry and Edman sequencing of peptides from the secreted aspartyl proteinase isoenzyme (Sap1) demonstrate that positions specified by the CTG codon contain a nonmodified serine (Ser) in Candida albicans.

Indexed as

Aspartic Acid EndopeptidasesCandida albicansCodonGenetic CodeLeucinePeptide FragmentsRNA, Transfer, SerSequence AnalysisSerineAspartic Acid EndopeptidasesCodonLeucinePeptide FragmentsRNA, Transfer, SerSAP1 protein, Candida albicansSerine

Identifiers

PMID7751316
PMCPMC176978
OpenAlexW1947722128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.