Evidence map›Paper›PMID 7749869›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology1995

The response-to-retention hypothesis of early atherogenesis.

K J Williams, I Tabas

Registry-linked trialAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02770872 (The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk), which is not on this map. Cited by 455 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
455citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02770872 completednot on this mapstarted 2014, after this paper: background citation

The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk

TypeobservationalSponsorLisa TannockRan2014 to 2018Enrolled19ConditionsCardiovascular DiseaseArmsObservation of SAA on apoB containing lipoproteins
3 · Its place in the literature

Who cites it

455 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Sphingolipids and Atherosclerosis.Current atherosclerosis reports · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. ApoB-specific CD4Frontiers in immunology · 2026
    Review
  20. Review

395 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

K J WilliamsDivision of Endocrinology and Metabolic Diseases, Thomas Jefferson University, Philadelphia, PA 19107-6799, USA.
I Tabas

Funding

VITAMIN A TRANSPORT AND RETINOL-BINDING PROTEIN METABOLISMP50HL021006 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · 1985 to 1996
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LIPOPROTEIN LIPASE AND ATHEROGENESISR01HL038956 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI WILLIAMS, KEVIN JON · 1994 to 1998
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ACAT REACTIVITY IN MACROPHAGESR01HL039703 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI TABAS, IRA A · 1988 to 1996
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METABOLISM OF A SYNTHETIC ANTI-ATHEROGENIC LIPOPROTEINR29HL038956 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI WILLIAMS, KEVIN JON · 1987 to 1991
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NHLBI NIH HHS HL21006NHLBI NIH HHS HL38956NHLBI NIH HHS HL39703NHLBI NIH HHS R01 HL038956
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Models, BiologicalAnimalsArteriesArteriosclerosisHumansLipoproteins, LDLProteoglycansLipoproteins, LDLProteoglycans

Identifiers

PMID7749869
PMCPMC2924812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.